A new entry to pyrano[3,2-f]indolizines via the regioselective formation of an indolizidin-7-one enamine

Article abstract of DOI:10.3987/com-95-7368

From indolizidin-7-one (1), the preparation of several (pyrrolidine, piperidine and morpholine) enamines was described. The isolation of one of them (morpholine) as a pure regioisomer allowed the synthesis of pyrano[3,2-f]-indolizines for which only a few examples were known.