Tetrahedron Letters p. 1855 - 1858 (2002)
Update date:2022-08-30
Topics:
Nishiyama, Yutaka
Hirose, Masaharu
Kitagaito, Wataru
Sonoda, Noboru
A catalytic synthetic method of 3,4-dihydroquinazolin-4-ones has been developed. When N-(2-nitrobenzoyl)amides were treated with carbon monoxide in the presence of a catalytic amount of selenium, reductive N-heterocyclization of N-(2-nitrobenzoyl)amide efficiently proceeded to give the corresponding 3,4-dihydroquinazolin-4-ones in moderate to good yields.
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