One-pot synthesis of 2-(2-hydroxyaryl)quinolines: Reductive coupling reactions of 2′-hydroxy-2-nitrochalcones

Article abstract of DOI:10.1016/S0040-4039(03)01374-1

A one-pot synthesis of novel 2-(2-hydroxyaryl)quinolines have been developed from the intramolecular reductive coupling reactions of 2′-hydroxy-2-nitrochalcones, induced by stannous chloride in acidic medium (HCl/AcOH). In some cases these transformations can be performed with ammonium formate/Pd-C in methanol.