Journal of Fluorine Chemistry p. 255 - 264 (1986)
Update date:2022-08-03
Topics:
Shiue, Chyhg-Yann
Wolf, A. P.
The reactions of gaseous acethyl hypofluorite with glycals (1a-d) followed by hydrolysis with 2N HCl give 2-deoxy-2-fluoro-D-glucose (2) and 2-deoxy-2-fluoro-D-mannose (3).The ratio of 2 to 3 depends largely on the polarity of the solvent rather than on the size of the substituents on the hydroxyl groups of glucal.The amount of 3 in the final product from the reaction of 1b-d with acethyl hypofluorite ranges from 4percent in non-polar solvents (Freon-11, CCl4, hexane) to ca. 20percent in polar solvents (HOAC, MeOH, DMF, acetone).
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Doi:10.1021/ja00947a026
(1965)Doi:10.1016/S0040-4020(01)92956-4
(1970)Doi:10.1016/S0040-4020(01)93025-X
(1970)Doi:10.1021/ol047867c
(2004)Doi:10.1021/acs.joc.7b01571
(2017)Doi:10.1021/jo00813a015
(1971)