Plant antitumor agents: Synthesis and biological activity of camptothecin analogues

DOI: 10.1021/jm00179a016

Source and publish data:

Journal of Medicinal Chemistry p. 554 - 560 (1980)

Update date:2022-08-17

Topics:

Authors:

Wani Wani

Ronman Ronman

Lindley Lindley

Wall Wall

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Article abstract of DOI:10.1021/jm00179a016

Four analogues, 10-methoxy (20), 12-aza (29), benz[j] (36), and 18-methoxy (38), of camptothecin were obtained by total synthesis. The two water-soluble analogues, 10-[(carboxymethyl)oxy] (24) and 10-[2'-(diethylamino)-ethoxy]-20(S)-camptothecin (26), wit

Full text of DOI:10.1021/jm00179a016

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