Successive 1,4- and 1,2-additions of organometallic reagents to a chiral binaphthyl ester: One step synthesis of optically active ketones

Article abstract of DOI:10.1016/0040-4039(91)80497-T

Organometallic reagents undergo a 1,4-addition onto the chiral binaphthyl ester of α,β-unsaturated carboxylic acid followed by the formal 1,2-addition to yield optically active ketones directly.