Sterically congested chiral N-acetyl 2-oxazolidinone as acetyl enolate equivalents in stereoselective aldol reactions

DOI: 10.1248/cpb.42.748

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Chemical and Pharmaceutical Bulletin p. 748 - 750 (1994)

Update date:2022-08-16

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Authors:

Otsuka Otsuka

Ishizuka

Kimura Kimura

Kunieda Kunieda

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Article abstract of DOI:10.1248/cpb.42.748

Sterically constrained and highly congested N-acetyl-DMAOx (1a) serves well as a useful chiral acetyl enolate equivalent which permits a diastereoselective and direct approach to 'acetate' aldols (2) including statine derivative.

Full text of DOI:10.1248/cpb.42.748

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