THE ENANTIOSPECIFIC SYNTHESIS OF (4S,5R)-AND (4S,5S)-4,5-DIHYDROXYDECANOIC ACID γ-LACTONES, PROPOSED AUTOREGULATORS FROM STREPTOMYCES GRISEUS

Article abstract of DOI:10.1016/S0040-4039(01)81567-7

Both the (4S,5R)- and (4S,5S)-isomers of 4,5-dihydroxydecanoic acid γ-lactone, natural products and proposed autoregulators of Streptomyces Griseus, have been synthesised directly and in high yield from D-ribose via a common intermediate.