Asymmetric synthesis of α-aminophosphonates via diastereoselective addition of phosphite to chiral imine derivatives

DOI: 10.1016/0957-4166(95)00411-4

Source and publish data:

Tetrahedron Asymmetry p. 21 - 24 (1996)

Update date:2022-08-30

Topics:

Authors:

Chung, Sung-Kee

Kang, Dong-Ho

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Article abstract of DOI:10.1016/0957-4166(95)00411-4

One pot three component reactions employing homochiral (1S)-(+)-camphorsulfon-amide-derived carbamate, aldehydes and diethyl phosphite at 0°C was found to give protected (S)-α-aminophosphonates in high enantiomeric purities.

Full text of DOI:10.1016/0957-4166(95)00411-4

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Product name:(S)-1-AMINO-BENZYL PHOSPHONIC ACID

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