Synthesis, modeling and binding affinity of an ester analogue of the terminal trisaccharide of the tumor-associated antigen globo H1

DOI: 10.1016/S0040-4020(98)01126-0

Source and publish data:

Tetrahedron p. 1469 - 1478 (1999)

Update date:2022-08-11

Topics:

Authors:

Canevari, Silvana

Colombo, Diego

Compostella, Federica

Panza, Luigi

Ronchetti, Fiamma

Russo, Giovanni

Toma, Lucio

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Article abstract of DOI:10.1016/S0040-4020(98)01126-0

The synthesis of the trisaccharide α-L-Fucp-(1→2)-β-D-Galp-(1→3)- β-D-Galp2AcOPr (3), mimicking the globo-H terminal trisaccharide unit (2), is described. The conformational properties of 3 were investigated with the aid of molecular mechanics energy mini

Full text of DOI:10.1016/S0040-4020(98)01126-0

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