Lewis acid- and cationic lithium-mediated diastereoselective aldol-type reaction based on a double chiral recognition manner for the asymmetric synthesis of α-substituted serines

DOI: 10.1016/0040-4039(95)00725-R

Source and publish data:

Tetrahedron Letters p. 4101 - 4104 (1995)

Update date:2022-08-30

Topics:

Authors:

Sano Sano

Liu Liu

Takebayashi

Kobayashi

Tabata Tabata

Shiro Shiro

Nagao Nagao

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Article abstract of DOI:10.1016/0040-4039(95)00725-R

Diastereoselective aldol-type reaction of ethyl (5R or 5S)-3,6-diethoxy-2,5-dihydro-5-isopropyl-2-pyrazinecarboxylate (5) with chiral aldehyde 7 was investigated by using Sn(OSO₂CF₃)₂-N-ethylpiperizine, MgBr₂-Et

Full text of DOI:10.1016/0040-4039(95)00725-R

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