Journal of Fluorine Chemistry p. 69 - 76 (1993)
Update date:2022-08-29
Topics:
Kurosawa, Shigeru
Sekiya, Akira
Arimura, Takashi
Yamada, Toshiro
Hydrofluorocarbons (HFCs) have been fluorinated via the high-valency metal fluorides CoF3, MnF3 and KCoF4.The fluorinating powers of these reagents for the monofluorination of 2,2-difluoropropane are in the order CoF3>MnF3>KCoF4.The fluorinations of fluorinated ethanes with CoF3 have been examined in detail.The effects of temperature and the distribution products are described.Furthermore, regioselective monofluorination of gem-difluoro compounds (C3-C5) with CoF3 was achieved at the methylene position adjacent to the gem-difluoro group.The trifluoro compounds were obtained in good yield at low reaction temperatures.
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