Improved synthesis of dihydrothebainone and its 14 β-epimer

Article abstract of DOI:10.1080/00397919808005110

An improved synthesis for the preparation of diastereomerically pure dihydrothebainone (1) from thebaine (3) is reported. A 41% overall yield was realized over three steps via direct transformation of dihydrothebaine-Φ (4) to thebainone-A (6) with 6N HCl.

Full text of DOI:10.1080/00397919808005110

Synthetic Communications
ISSN: 0039-7911 (Print) 1532-2432 (Online) Journal homepage: http://www.tandfonline.com/loi/lsyc20
Improved Synthesis of Dihydrothebainone and Its
14 β-Epimer
Marian R. Davidson & Brian T. Gregg
To cite this article: Marian R. Davidson & Brian T. Gregg (1998) Improved Synthesis of
Dihydrothebainone and Its 14 β-Epimer, Synthetic Communications, 28:3, 547-558, DOI:
10.1080/00397919808005110
To link to this article: http://dx.doi.org/10.1080/00397919808005110
Published online: 15 Aug 2006.
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Date: 08 April 2016, At: 01:56