(1)H NMR Investigations on the Conformation of the Spirodioxolanes Derived from Vicinal Diols II-The Ketal of Cyclohexanone and Racemic 1,2-Propanediol

Article abstract of DOI:10.1002/mrc.1270180308

The methylene, methine and methyl protons at C- and C- from the dioxolane miety in 2-methyl-1,4-dioxaspiro<4.5>decane constitute an ABMX3 coupling system.The analysis data obtained and, also, the application of the Karplus rule to the value of the J(AB) vicinal coupling constant, confirm the axial orientation of the A methine proton and the pseudoequatirial orientation of the B methylene proton.These findings agree with a 'half-chair'conformation of the 1,3-dioxolane ring.