Journal of Natural Products p. 987 - 995 (2015)
Update date:2022-08-22
Topics:
Li, Bo
Ni, Yang
Zhu, Ling-Juan
Wu, Feng-Bo
Yan, Fei
Zhang, Xue
Yao, Xin-Sheng
Seven new flavonoid glycosides (1-7), matteflavosides A-G, together with 12 known flavonoids (8-19) were isolated from the rhizomes of Matteuccia struthiopteris (L.) Todar. Their structures were established via the analyses of extensive spectroscopic data. All compounds were evaluated for their anti-influenza virus (H1N1) activity using the neuraminidase inhibition assay. The results showed that compound 7 exhibited significant inhibitory activity against the H1N1 influenza virus neuraminidase with an EC50 value of 6.8 ± 1.1 μM and an SI value of 34.4, and compounds 8 and 17 showed moderate inhibitory activity.
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