First practical and efficient synthesis of 3-phosphorylated β-carboline derivatives using the Pictet-Spengler reaction

Article abstract of DOI:10.1002/ejoc.201403418

We report here the first practical and efficient synthesis of the diethyl 1,2,3,4-tetrahydro-β-carboline-3-phosphonates 3 and 4 as well as diethyl 9H-β-carboline-3-phosphonates 5 and 6. The target compounds were prepared in good yields by application of t