Chemical Communications p. 9910 - 9913 (2017)
Update date:2022-08-30
Topics:
Yan, Jin-Wu
Zhu, Jia-Ying
Zhou, Kai-Xiang
Wang, Jin-Sheng
Tan, Hui-Ya
Xu, Zhong-Yong
Chen, Shuo-Bin
Lu, Yu-Ting
Cui, Meng-Chao
Zhang, Lei
Two neutral merocyanine-based near-infrared fluorescent probes were for the first time developed through rational engineering of the classical cationic cyanine scaffold IR-780 for in vivo imaging of amyloid-β plaques. In vivo NIRF imaging revealed that the probe could penetrate the blood-brain barrier and efficiently differentiate the living transgenic and wild-type mice.
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(2017)
