Synthesis of 3-benzoylcyclohexanone, a key intermediate for the synthesis of ketoprofen

Article abstract of DOI:10.1080/00397919408012628

A simple and convenient synthesis of 3-benzoylcyclohexanone, a ketoprofen precursor, is proposed. It consists of the preparation of 5-trimethylsilyl-3-cyclohexenone via disilylation of anisole followed by hydrolysis and subsequent regiospecific benzoylati

Full text of DOI:10.1080/00397919408012628

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Synthetic Communications: An
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Organic Chemistry
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Synthesis of 3-
Benzoylcyclohexanone, A key
Intermediate for the Synthesis
of Ketoprofen
Bernard Bennetau a , Michele Krempp a & J.
Dunoguès a
a Laboratoire de Chimie Organique et
Organométallique , URA 35, Université Bordeaux
I, 351 Cours de la Libération, F-33405, Talence,
Cédex, France
Published online: 23 Sep 2006.
To cite this article: Bernard Bennetau , Michele Krempp & J. Dunoguès
(1994) Synthesis of 3-Benzoylcyclohexanone, A key Intermediate for the
Synthesis of Ketoprofen, Synthetic Communications: An International Journal
for Rapid Communication of Synthetic Organic Chemistry, 24:1, 77-83, DOI:
10.1080/00397919408012628
To link to this article: http://dx.doi.org/10.1080/00397919408012628
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