Tetrahedron Letters p. 7811 - 7814 (1998)
Update date:2022-08-10
Topics:
Nieuwenhuijzen, Jose W.
Conti, Paolo G. M.
Ottenheijm, Harry C. J.
Linders, Joannes T. M.
An efficient parallel synthesis of ureas based on amino acids is described, both in solution and on solid phase. 1,1'- Carbonylbisbenzotriazole 2 is used as the coupling reagent. The ureas 5 and 10 were obtained in high yield (80-100%) and purity (71-97%).
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