Synthesis of optically active lipopeptide analogs from the outer membrane of Escherichia coli

DOI: 10.1248/cpb.39.2590

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 2590 - 2596 (1991)

Update date:2022-08-03

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Authors:

Kurimura

Takemoto

Achiwa Achiwa

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Article abstract of DOI:10.1248/cpb.39.2590

The synthesis of optically active lipopeptide derivatives has been accomplished by the use of chiral glycerol derivatives. Lipopeptide derivatives with (R)-glycerol moieties showed higher mitogenic activities than those with the (S)-configuration. N-2,2,2-Trichloroethoxycarbonyl lipopeptide derivatives increased mitogenic activity.

Full text of DOI:10.1248/cpb.39.2590

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