IspC as target for antiinfective drug discovery: Synthesis, enantiomeric separation, and structural biology of fosmidomycin thia isosters

DOI: 10.1021/jm4012559

Source and publish data:

Journal of Medicinal Chemistry p. 8151 - 8162 (2013)

Update date:2022-08-10

Topics:

Authors:

Kunfermann, Andrea

Lienau, Claudia

Illarionov, Boris

Held, Jana

Gr?wert, Tobias

Behrendt, Christoph T.

Werner, Philipp

H?hn, Saskia

Eisenreich, Wolfgang

Riederer, Ulrich

Mordmüller, Benjamin

Bacher, Adelbert

Fischer, Markus

Groll, Michael

Kurz, Thomas

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Article abstract of DOI:10.1021/jm4012559

The emergence and spread of multidrug-resistant pathogens are widely believed to endanger human health. New drug targets and lead compounds exempt from cross-resistance with existing drugs are urgently needed. We report on the synthesis and properties of

Full text of DOI:10.1021/jm4012559

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