PREPARATION D'ALKYL-4 γ-LACTONES INSATUREES OPTIQUEMENT PURES. APPLICATION A LA SYNTHESE DE LA (+) TETRAHYDROCERULENINE

Article abstract of DOI:10.1016/S0040-4039(00)77824-5

Optically pure enantiomers of unsaturated 4-alkyl γ-lactones are synthesized from optically active propargylic carbinols obtained by asymmetric reduction of α-acetylenic ketones with the complex . (+) Tetrahydrocerulenin is prepared from the butenolide 6 obtained by this way.