SYNTHESIS OF AZASPIROCYCLIC COMPOUNDS VIA ORGANOIRON COMPLEXES. POTENTIAL SYNTHETIC ROUTES TO HISTRIONICOTOXIN AND CEPHALOTAXUS ALKALOIDS

Article abstract of DOI:10.1016/0040-4039(80)80094-3

Reaction of cyclohexadienylium-Fe(CO)3 complexes (7) and (8) with sodiomalononitrile gives the carbo-spirocyclic derivatives (9) and (10), whilst reaction with benzylamine and removal of iron leads to the azaspirocyclic enones (15) and (16), respectively.