14
J. A. Hyatt
8. Campbell, S.; Stone, W.; Whaley, S.; Krishnan, K. Development of gamma-
tocopherol as a colorectal cancer chemopreventative agent. Crit. Rev. Oncol./
Hematol. 2003, 47, 249–259.
9. Shah, S.; Sylvester, P. W. g-Tocopherol inhibits neoplastic mammary epithelial
cell proliferation by decreasing Akt and nuclear factor kB activity. Exper. Biol.
Med. 2005, 230, 235–241.
10. Theriault, A.; Chao, J.-T.; Wang, Q.; Gapor, A.; Adeli, K. Tocotrienol: A review of
its therapeutic potential. Clin. Biochem. 1999, 32, 309–319.
11. Chenevert, R.; Courchesne, G. Synthesis of (S)-a-tocotrienol via an enzymatic
desymmetrization of an achiral chroman derivative. Tetrahedron Lett. 2002, 43,
7971–7973.
12. Trost, B. M.; Shen, H. C.; Dong, L.; Surivet, J.-P.; Sylvain, C. Synthesis of chiral
chromans by the Pd-catalysed asymmeteric allylic alkylation (AAA): Scope,
mechanism, and applications. J. Am. Chem. Soc. 2004, 126, 11966–11983.
13. Gu, F.; Netscher, T.; Atkinson, J. 5-Trideuteromethyl-a-tocotrienol and 5-14CH3-
a-tocotrienol as biological tracers of tocotrienols. J. Label. Compd. Radiopharm.
2006, 49, 733–743.
14. Mazzini, F.; Netscher, T.; Salvadori, P. Easy route to labelled and unlabelled
R,R,R-g-tocopherol by aryl demethylation of a-homologues. Tetrahedron 2005,
61, 813–817.
15. Buyukkidan, B.; Bilgic, S.; Bilgoc, O. The synthesis of some chromans via
o-quinone-methide intermediates. Synth. Commun. 2001, 31, 1263–1270.
16. Tanaka, T.; Kyuuko, Y.; Hidaka, T. Process for producing chroman compound
from phenol or derivative thereof, olefin, and formaldehyde. PCT Patent WO
2005073212, CAN 143:211840, 2005.
17. Rosenau, T.; Habicher, W. D. Novel tocopherol compounds, 1: bromination of
a-tocopherol: mechanism and synthetic applications. Tetrahedron 1995, 51,
7919–7923.
18. Baird, M. C. Decarbonylation reactions of acid halides and aldehydes. In The
Chemistry of the Functional Groups, Supplementary Vol. B: Acid Derivatives;
Patai, S. Ed.; Wiley: New York, 1979; pp. 825–857.
19. Ohno, K.; Tsuji, J. Organic syntheses by means of noble metal compounds,
XXXV: novel decarbonylation reactions of aldehydes and acyl halides using
rhodium complexes. J. Am. Chem. Soc. 1968, 90, 99–107.
20. Castellani, C.; Carugo, O.; Giusti, M.; Leopizzi, C.; Perotti, A.; Invernizzi
Gamba, A.; Vidari, G. Scandium trifluoromethanesulfonate as an active catalyst
in the decarbonylation of aromatic aldehydes. Tetrahedron 1996, 52,
11045–11052.
21. Hawthorne, J. O.; Wilt, M. H. Decarbonylation of aromatic aldehydes. J. Org.
Chem. 1960, 25, 2215–2216.
22. Palozza, P.; Piccioni, E.; Avanzi, L.; Vertuani, S.; Calviello, G.; Manfredini, S.
Design, synthesis, and antioxidant activity of FeAOX-6, a novel agent deriving
from a molecular combination of the chromanyl and polyisoprenyl moieties.
Free Rad. Biol. Med. 2002, 33, 1724–1735.