KOtBu-promoted three-component coupling of aldehydes and alkynes: Highly efficient synthesis of 1-En-4-yn-3-ols and 2-En-4-yn-1-ols

DOI: 10.1021/jo0604078

Source and publish data:

Journal of Organic Chemistry p. 4343 - 4345 (2006)

Update date:2022-08-28

Topics:

Authors:

Wang, Shao-Hua

Tu, Yong-Qiang

Chen, Peng

Hu, Xiang-Dong

Zhang, Fu-Min

Wang, Ai-Xia

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Article abstract of DOI:10.1021/jo0604078

A KO^tBu-promoted three-component coupling reaction of aldehydes and alkynes without a transition-metal catalyst was developed in which the sequential addition/isomerization/addition processes take place in one pot. This reaction could be develo

Full text of DOI:10.1021/jo0604078

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