Isomeric N-methyl-7-deazaguanines: Synthesis, structural assignment, and inhibitory activity on xanthine oxidase

Article abstract of DOI:10.1021/jm00374a008

The N-methyl isomers of 2-amino-3,7-dihydro-4H-pyrrolo[2,3-d]pyrimidin-4-one¹ (2a) have been synthesized regiospecifically and their structures assigned. The 3-methyl thylcompound was obtained by alkylation of the parent chromophore 2a with dim