Journal of Organic Chemistry p. 7480 - 7487 (2019)
Update date:2022-08-10
Topics:
Song, Dan
Wang, Chao-Ming
Ye, Zhi-Peng
Xia, Peng-Ju
Deng, Zhi-Xiong
Xiao, Jun-An
Xiang, Hao-Yue
Yang, Hua
A general and straightforward protocol for di-/perfluoroalkylation of ortho-hydroxycinnamic esters via a photoredox-catalyzed cascade was developed to access a variety of 3-fluoroalkylated coumarins. This method was characterized by all-in-one synthetic design, simplified operation, mild reaction conditions, and broad substrate scope. Moreover, a sequential one-pot procedure starting from commercially available salicylaldehyde was also successfully realized to synthesize 3-fluoroalkylated coumarins.
View MoreContact:+86-21-56338808
Address:799 Dunhuang Road, Putuo
Wuhan Konberd Biotech Co., Ltd.
Contact:+86-27-87205925
Address:NO.666, Gaoxin Road, Eastlake High-tech zone
Sichuan Sangao Biochemical Co., Ltd
Contact:+86-28-84874233
Address:19F, Bldg.2, Shudu Center, Tianfu 2nd St., Hi-tech zone, Chengdu 610041, Sichuan Province, China.
HUNAN CHEMAPI BIOLOGICAL TECHNOLOGY CO.,LTD.
Contact:+86-186-02659358
Address:1004, building 3, Wanke Jinsemaitianyuan, 498 Guitang Road, Yuhua District, Changsha City, Hunan Province, China
Quzhou Ruiyuan chemical Co., Ltd
Contact:+86-570-3039321/3039361/3039308
Address:18# Huayang Road,Quzhou High-tech Industrial Park, Zhejiang China.
Doi:10.1021/ja00387a034
(1982)Doi:10.1016/S0022-328X(01)01035-X
(2002)Doi:10.1021/acs.jmedchem.9b02151
(2020)Doi:10.1111/1468-0289.00166
(1881)Doi:10.1039/b009944i
(2001)Doi:10.1039/c3ra44662j
(2014)