219. Cob(I)alamin-Catalyzed Skeletal Migrations Observed during the Reduction of 4β-(tert-Butyl)-1α-(1-methylvinyl)cyclohexanecarbaldehyde

Article abstract of DOI:10.1002/hlca.19840670726

The cob(I)alamin(1(I))-catalyzed transformation of the aldehyde 2 has been studied (cf.Table 1).Kinetic examinations showed a rapid isomerization of 2 to 3 (cf.Fig. 1 and 2).From the transformations in glacial AcOH, the two cyclopropanols 5 and 7 were iso