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Hydroxyethyl starch

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Name

Hydroxyethyl starch

EINECS
CAS No. 9005-27-0 Density
Solubility Melting Point
Formula C2H6O2.xUnspecified Boiling Point 878.8°C at 760 mmHg
Molecular Weight 0 Flash Point 485.3°C
Transport Information Appearance
Safety Risk Codes
Molecular Structure Molecular Structure of 9005-27-0 (Hydroxyethyl starch) Hazard Symbols
Synonyms

Bohramyl;Hespander;Polaris Gum LV;Bohramyl CR;Penford 460;PG 280;Oxethamyl;Volex;Hetastarch;PG 380;Essex Gum 1360;Ethylex 3095;Ethylex 2020;QYH 1;Pentafraction;HAES-steril;Elohes;Hespan;Ethylex 2030;Pentastarch;Penford 280;Penford 290;Penford 295;Coatmaster K;Penford 270;Penford 200;Penford 260;Penford P 208;Pen-Cote;Polaris Gum;Plasmasteril;Amaizo 742D;Ethylex 2025;Amaizo 745D;Clineo 712D;Unique Gum 3010;Hydroxyethyl Starch130/0.4;Hydroxyethyl Starch 20/40/130/200;Hydroxyethyl Starch 130/0.4;Hydroxyethyl Starch(130/0.4);

 

Hydroxyethyl starch Consensus Reports

Reported in EPA TSCA Inventory.

Hydroxyethyl starch Specification

The systematic name of Hydroxyethyl starch is Starch, 2-hydroxyethyl ether. With the CAS registry number 9005-27-0, it is also named as 2-Hydroxyethyl starch ether. The product's categories are Carbohydrates; Carbohydrates A to; Carbohydrates H-LBiochemicals and Reagents; Polysaccharide, and the other registry numbers are 115252-32-9; 204144-00-3; 39363-84-3; 39363-85-4; 62253-20-7; 73666-73-6; 87140-13-4; 9057-07-2; 936087-55-7; 936087-60-4. Besides, it is a nonionic starch derivative.

Uses of Hydroxyethyl starch: because it can increase the blood volume, allowing red blood cells to continue to deliver oxygen to the body. This chemical can be used to prevent shock following severe blood loss caused by trauma, surgery, or some other problem.

The toxicity data is as follows:

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal > 300gm/kg (300000mg/kg)   Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 16, Pg. 431, 1974.
mouse LD50 intravenous 20300mg/kg (20300mg/kg) BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) Oyo Yakuri. Pharmacometrics. Vol. 6, Pg. 1023, 1972.
mouse LD50 oral > 12gm/kg (12000mg/kg)   Oyo Yakuri. Pharmacometrics. Vol. 6, Pg. 1023, 1972.
mouse LD50 subcutaneous > 18gm/kg (18000mg/kg)   Oyo Yakuri. Pharmacometrics. Vol. 6, Pg. 1023, 1972.
rabbit LD50 intravenous 8460mg/kg (8460mg/kg)   Drugs in Japan Vol. -, Pg. 1007, 1995.
rat LD50 intraperitoneal > 300gm/kg (300000mg/kg)   Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 16, Pg. 431, 1974.
rat LD50 intravenous 8280mg/kg (8280mg/kg)   Drugs in Japan Vol. -, Pg. 1007, 1995.
rat LD50 oral > 50gm/kg (50000mg/kg)   Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 16, Pg. 431, 1974.
rat LD50 subcutaneous > 18gm/kg (18000mg/kg)   Oyo Yakuri. Pharmacometrics. Vol. 6, Pg. 1023, 1972.

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