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| CAS No.: | 9004-64-2 |
|---|---|
| Name: | Hydroxypropyl cellulose |
| Molecular Structure: | |
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| Formula: | C36H70O19 |
| Molecular Weight: | 59.08708 |
| Synonyms: | Cellulose,ethers,2-hydroxypropyl ether;Klucel 99GF-EP;L-HPC-LH 21;Klucel LF;L-HPC-LH 41;L-HPC LH 11;JK 491;Klucel HW;Klucel MF;Klucel G;Klucel KL;HPC-MG;EF 10 (cellulose derivative);Klucel E;Klucel SR;Cellulose,polymerspolymer with methyloxirane ;; see;Klucel M;PM 50 (polymer);HPC-EF-G;HPC-MF;Klucel H;Fuji HEC-SG 25F;also Cellulose,ethers,2-hydroxypropyl ether;Nisso HPC;Klucel;HPC-L;HPC-S;LHPC 21;HPC-M;Klucel EEL;Klucel HXF;Metolose LE-G;G 4000HXL;HPC-H;Klucel Gf;TSK-Gel G 2000HXL;L-HPC-LH 31;HPC-E (cellulose derivative);Klucel 99E;Klucel 99G;HPC-SL;Nisso HPC-L;Klucel JF;Klucel L;Nisso HPC-SL;LH 31;Klucel J;Klucel EF;Klucel HF;HPC-LG;Klucel 99M;L-HPC-LH 22;Klucel HF-NF;HPC-LE-G;Hyprolose;L-HPC;High-Substituted Hydroxyproxyl Cellulose(H-HPC);Hydroxy Propyl Cellulose;Hydroxypropylcellulose;HYDROXYPROPYL ETHER of CELLULOSE;Hydroxypropyl cellulose,9004-64-2;Hydroxypropyl Cellulose(HPC); |
| EINECS: | 220-971-6 |
| Density: | 1.27 g/cm3 |
| Melting Point: | 371.06 °C |
| Boiling Point: | 891.2 ºC at 760 mmHg |
| Flash Point: | 492.8 ºC |
| Solubility: | Soluble in polar organic solvents, in water at room temperature.Soluble in water, methyl alcohol, ethyl alcohol and other organic solvents. |
| Appearance: | white powder |
| Safety: | A poison by intravenous route. Slightly toxic by ingestion. When heated to decomposition it emits acrid smoke and fumes. |
| PSA: | 0.00000 |
| LogP: | 0.00000 |
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Specification
The Hydroxypropyl cellulose, with the cas registry number 9004-64-2, has the systematic name of Cellulose, 2-hydroxypropyl ether. Its product categories are various, including Cellulose; Natural Polymers; Polymer Science; HU - HZPolymer Standards; Hydroxypropyl cellulose; Water Soluble Polymers; Alphabetic; H; API's. What's more, this chemical could be produced by the reaction of alkali and epoxypropane. This is a kind of white particle or fabrous powder with no odour but with thermoplasticity. It is soluble in ehanol while insoluble in diethyl ether and could become transparent to oyster white viscoloid colloidal solution. Besides, this chemical is stable chemically but combustible and incompatible with strong oxidizing agents. While using this chemical, please do avoid contacting with skin and eyes.
Uses of Hydroxypropyl cellulose:
It is widely applied in many fields. It could be usually used in pharmaceutic for being the cementing agent and membrance-forming agent in medicines; It could also be used as the film-forming agent, dispersing agent, stabilizing agent and thickening agent in cosmetic, painting and printing ink industries.
The toxicity data of Hydroxypropyl cellulose is as follows:
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| mouse | LD50 | intraperitoneal | > 25gm/kg (25000mg/kg) | Oyo Yakuri. Pharmacometrics. Vol. 4, Pg. 1013, 1970. | |
| mouse | LD50 | intravenous | > 500mg/kg (500mg/kg) | Oyo Yakuri. Pharmacometrics. Vol. 4, Pg. 1013, 1970. | |
| mouse | LD50 | oral | > 5gm/kg (5000mg/kg) | Oyo Yakuri. Pharmacometrics. Vol. 4, Pg. 1013, 1970. | |
| rat | LD50 | intraperitoneal | > 25gm/kg (25000mg/kg) | Oyo Yakuri. Pharmacometrics. Vol. 4, Pg. 1013, 1970. | |
| rat | LD50 | intravenous | 250mg/kg (250mg/kg) | Oyo Yakuri. Pharmacometrics. Vol. 4, Pg. 1013, 1970. | |
| rat | LD50 | oral | 10200mg/kg (10200mg/kg) | FAO Nutrition Meetings Report Series. Vol. 46A, Pg. 131, 1969. |
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