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| Name |
Hypoglycine B |
EINECS | N/A |
| CAS No. | 502-37-4 | Density | 1.33g/cm3 |
| PSA | 133.21000 | LogP | 1.25470 |
| Solubility | N/A | Melting Point |
194-195°, 200-206° |
| Formula | C12H18 N2 O5 | Boiling Point | 592.8°Cat760mmHg |
| Molecular Weight | 270.285 | Flash Point | 312.3°C |
| Transport Information | N/A | Appearance | N/A |
| Safety | Poison by intravenous route. An experimental teratogen. Other experimental reproductive effects. When heated to decomposition it emits toxic fumes of NOx. | Risk Codes | N/A |
| Molecular Structure |
|
Hazard Symbols | N/A |
| Synonyms |
Alanine,L-g-glutamyl-3-[(1R)-methylenecyclopropyl]-(9CI); Alanine, N-L-g-glutamyl-3-(methylenecyclopropyl)-, (R)-; Glutamine,N-[1-carboxy-2-(methylenecyclopropyl)ethyl]- (7CI); Hypoglycine B (6CI,8CI);Hypoglycin B; g-L-Glutamyl-a-amino-b-(2-methylenecyclopropyl)propionicacid |
Hypoglycine B Chemical Properties
IUPAC Name: (2S)-2-Amino-5-[[2-hydroxy-1-[[(1R)-2-methylenecyclopropyl]methyl]-2-oxo-ethyl]amino]-5-oxo-pentanoic acid
Synonyms of Hypoglycine B (CAS NO.502-37-4) : g-L-Glutamyl-a-amino-b-(2-methylenecyclopropyl)propionic Acid Dipeptide ; g-L-Glutamylhypoglycine ; Hypoglycine B
CAS NO: 502-37-4
Molecular Formula:C12H18N2O5
Molecular Weight :270.2817
Molecular Structure :.png)
Index of Refraction: 1.562
Surface Tension: 61.7 dyne/cm
Density: 1.33 g/cm3
Flash Point: 312.3 °C
Enthalpy of Vaporization: 96.56 kJ/mol
Boiling Point: 592.8 °C at 760 mmHg
Vapour Pressure: 1.38E-15 mmHg at 25°C
Hypoglycine B Uses
Hypoglycine B (CAS NO.502-37-4) is toxic if ingested and is a causative agent of Jamaican Vomiting Sickness. It is an amino acid and chemically related to lysine.
Hypoglycine B Production
Hypoglycin B is a naturally occurring organic compound in the species Blighia sapida. It is particularly concentrated in the fruit of the plant especially in the seeds.
Hypoglycine B Toxicity Data With Reference
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| mouse | LDLo | intravenous | 160mg/kg (160mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: ATAXIA LUNGS, THORAX, OR RESPIRATION: DYSPNEA | Journal of Pharmacology and Experimental Therapeutics. Vol. 121, Pg. 272, 1957. |
| rabbit | LDLo | intravenous | 25mg/kg (25mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: ATAXIA ENDOCRINE: HYPOGLYCEMIA | Journal of Pharmacology and Experimental Therapeutics. Vol. 121, Pg. 272, 1957. |
| rat | LDLo | intravenous | 200mg/kg (200mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: ATAXIA LUNGS, THORAX, OR RESPIRATION: DYSPNEA | Journal of Pharmacology and Experimental Therapeutics. Vol. 121, Pg. 272, 1957. |
Hypoglycine B Safety Profile
Poison by intravenous route. An experimental teratogen. Other experimental reproductive effects. When Hypoglycine B (CAS NO.502-37-4) is heated to decomposition,S37/39:Wear suitable gloves and eye/face protection. it emits toxic fumes of NOx.
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