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Isoflupredone acetate

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Name

Isoflupredone acetate

EINECS 206-423-9
CAS No. 338-98-7 Density 1.32 g/cm3
PSA 100.90000 LogP 2.22050
Solubility N/A Melting Point 244-246° (dec)
Formula C23H29FO6 Boiling Point 576.5 °C at 760 mmHg
Molecular Weight 420.478 Flash Point 302.5 °C
Transport Information N/A Appearance N/A
Safety Risk Codes N/A
Molecular Structure Molecular Structure of 338-98-7 (21-Acetoxy-9-fluoro-11b,17-dihydroxypregna-1,4-diene-3,20-dione) Hazard Symbols N/A
Synonyms

Pregna-1,4-diene-3,20-dione,9-fluoro-11b,17,21-trihydroxy-, 21-acetate(6CI,7CI,8CI);21-Acetoxy-9-fluoro-11b,17-dihydroxypregna-1,4-diene-3,20-dione;9-Fluoro-11b,17,21-trihydroxypregna-1,4-diene-3,20-dione21-acetate;9-Fluoroprednisolone 21-acetate;9-Fluoroprednisolone acetate;9a-Fluoro-11b,17a,21-trihydroxypregna-1,4-diene-3,20-dione 21-acetate;9a-Fluoroprednisolone 21-acetate;9a-Fluoroprednisolone acetate;Predef;Predef R 2X;

Article Data 19

Isoflupredone acetate Specification

The IUPAC name of Isoflupredone acetate is [2-[(8S,9R,10S,11S,13S,14S,17R)-9-fluoro-11,17-dihydroxy-10,13-dimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] acetate . With the CAS registry number 338-98-7, it is also named as 9-Fluoro-11beta,17,21-trihydroxypregna-1,4-diene-3,20-dione 21-acetate ; 9-Fluoroprednisolone 21-acetate ; 9-Fluoroprednisolone acetate ; 9-Fluorprednisolone acetate ; 9alpha-Fluoroprednisolone acetate ; Isoflupredone 21-acetate ; NSC 37977 ; Predef ; Predef (Veterinary) ; Predef 2X ; Prednisolone, 9-fluoro-, 21-acetate ; U 6013 ; UNII-55P9TUL75S ; Pregna-1,4-diene-3,20-dione, 21-(acetyloxy)-9-fluoro-11,17-dihydroxy-, (11beta)- ; Pregna-1,4-diene-3,20-dione, 9-fluoro-11-beta,17,21-trihydroxy-, 21-acetate ; Pregna-1,4-diene-3,20-dione, 9-fluoro-11beta,17,21-trihydroxy-, 21-acetate (8CI) . The product's classification code are anti-inflammatory, hormone and reproductive effect.

 Isoflupredone acetate is pharmaceutical raw materials and intermediates. It also can be used in clinical treatment. Scientist have done a lot of experiments to confirm the following result. Hypokalemia should be considered in the differential diagnosis for cows that are weak or recumbent, particularly after treatment for ketosis with isoflupredone acetate.

 Isoflupredone acetate is 14 times as potent as hydrocortisone as an anti-inflammatory steroid as measured by the cotton pellet implantation assay which has been reported by research workers. Isoflupredone acetate markedly inhibits inflammatory reaction through its controlling influence on connective tissue and vascular components. Topically applied isoflupredone acetate is rapidly effective. The inflammatory response may also be effectively inhibited by isoflupredone acetate In ulcerations of the ear flaps, irritated lesions of the skin, and otitis externa, wounds of the concha. Chronic conditions respond more slowly and relapses are more frequent.

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