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CAS No. 74103-06-3 Density 1.398 g/cm3
Solubility Melting Point 160-161 ºC
Formula C15H13NO3 Boiling Point 223.7 ºC at 760 mmHg
Molecular Weight 255.27 Flash Point 89.1 ºC
Transport Information Appearance white crystalline or white powder
Safety Risk Codes
Molecular Structure Molecular Structure of 74103-06-3 (Ketorolac) Hazard Symbols

1H-Pyrrolizine-1-carboxylicacid, 5-benzoyl-2,3-dihydro-, (?à)-;1H-Pyrrolizine-1-carboxylicacid, 5-benzoyl-2,3-dihydro-;(+-)-5-Benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid;(+-)-Ketorolac;


Ketorolac Chemical Properties

IUPAC Name: 5-Benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid
Molecular Formula: C15H13NO3
Molecular Weight: 255.27 g/mol
SMILES: n12c([C@@H](C(O)=O)CC2)ccc1C(c1ccccc1)=O
InChI: InChI=1/C15H13NO3/c17-14(10-4-2-1-3-5-10)13-7-6-12-11(15(18)19)8-9-16(12)13/h1-7,11H,8-9H2,(H,18,19)
Classification Code: Analgesics; Analgesics, Non-Narcotic; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Cyclooxygenase Inhibitors; Drug / Therapeutic Agent; Enzyme Inhibitors; Peripheral Nervous System Agents; Sensory System Agents
Product Categories: API's
Index of Refraction: 1.436 
Molar Refractivity: 30.52 cm
Molar Volume: 116.6 cm3 
Polarizability: 12.1×10-24 cm3 
Surface Tension: 28.4 dyne/cm 
Density: 1.398 g/cm3 
Flash Point: 89.1 °C 
Enthalpy of Vaporization: 46.02 kJ/mol 
Boiling Point: 223.7 °C at 760 mmHg 
Melting Point: 160-161 °C
Vapour Pressure of Ketorolac (CAS NO.74103-06-3): 0.0947 mmHg at 25 °C

Ketorolac Uses

 Ketorolac (CAS NO.74103-06-3) is a non-steroidal anti-inflammatory drug, often used as an analgesic, antipyretic (fever reducer), and anti-inflammatory. An ophthalmic (i.e., eye-drop) solution of Ketorolac is available and is used to treat eye pain and to relieve the itchiness and burning of seasonal allergies.

Ketorolac Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 oral 200mg/kg (200mg/kg)   Agents and Actions, A Swiss Journal of Pharmacology. Vol. 12, Pg. 684, 1982.
mouse LDLo intraperitoneal 100mg/kg (100mg/kg)   Agents and Actions, A Swiss Journal of Pharmacology. Vol. 12, Pg. 684, 1982.

Ketorolac Safety Profile

RIDADR: 3249
HazardClass: 6.1(a)
PackingGroup of Ketorolac (CAS NO.74103-06-3): II

Ketorolac Specification

 Ketorolac (CAS NO.74103-06-3), its Synonyms are (+-)-5-Benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid ; (+-)-Ketorolac ; Ketorolacum ; 1H-Pyrrolizine-1-carboxylic acid, 2,3-dihydro-5-benzoyl-, (+-)- .

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