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Lentinan

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Name

Lentinan

EINECS 1806241-263-5
CAS No. 37339-90-5 Density 1.88g/cm3
PSA 0.00000 LogP 0.00000
Solubility Melting Point
Formula (C42H70O35)n Boiling Point 1472°C at 760 mmHg
Molecular Weight 0 Flash Point 844°C
Transport Information Appearance Yellow Fine Powder
Safety Risk Codes
Molecular Structure Molecular Structure of 37339-90-5 (Lentinan) Hazard Symbols
Synonyms

Biomoduline;LC 33;

 

Lentinan Specification

The Lentinan is an organic compound with the formula (C42H70O35)n. The IUPAC name of this chemical is (2R,3R,4S,5S,6R)-2-[[(2R,3R,4S,5R,6R)-4-[(2S,3R,4S,5R,6R)-4-[(2S,3R,4S,5R,6R)-4-[(2S,3R,4S,5R,6R)-3,5-dihydroxy-4-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-6-[[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]oxan-2-yl]oxy-3,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3,5,6-trihydroxyoxan-2-yl]methoxy]-6-(hydroxymethyl)oxane-3,4,5-triol. With the CAS registry number 37339-90-5, it is also named as Bromoduline. The product's category is Natural Plant Extract. Besides, it is an intravenously administered anti-cancer agent. Lentinan is one of the host-mediated anti-cancer drugs which has been shown to affect host defense immune systems. It is extracted from the mushroom. 

The toxicity data is as follows:

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
dog LD50 intravenous > 100mg/kg (100mg/kg)   Drugs in Japan Vol. -, Pg. 1277, 1990.
monkey LD50 intravenous > 100mg/kg (100mg/kg)   Drugs in Japan Vol. -, Pg. 1277, 1990.
mouse LD50 intraperitoneal > 2500mg/kg (2500mg/kg)   Drugs in Japan Vol. -, Pg. 1277, 1990.
mouse LD50 intravenous 250mg/kg (250mg/kg)   Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 17, Pg. 365, 1986.
mouse LD50 subcutaneous > 2500mg/kg (2500mg/kg)   Drugs in Japan Vol. -, Pg. 1277, 1990.
rabbit LD50 intravenous > 100mg/kg (100mg/kg)   Drugs in Japan Vol. -, Pg. 1277, 1990.
rat LD50 intraperitoneal > 2500mg/kg (2500mg/kg)   Drugs in Japan Vol. -, Pg. 1277, 1990.
rat LD50 intravenous 250mg/kg (250mg/kg)   Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 17, Pg. 365, 1986.
rat LD50 subcutaneous > 2500mg/kg (2500mg/kg)   Drugs in Japan Vol. -, Pg. 1277, 1990.

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