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Lunamycin

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Name

Lunamycin

EINECS N/A
CAS No. 1149-99-1 Density 1.34g/cm3
PSA 77.76000 LogP 0.71630
Solubility N/A Melting Point 124-126℃
Formula C15H20 O4 Boiling Point 509.6°Cat760mmHg
Molecular Weight 264.321 Flash Point 276.1°C
Transport Information N/A Appearance N/A
Safety Poison by intravenous route. Mutation data reported. When heated to decomposition it emits acrid smoke and irritating fumes. Risk Codes N/A
Molecular Structure Molecular Structure of 1149-99-1 (illudin S) Hazard Symbols N/A
Synonyms

Illudin S(6CI,7CI); Spiro[cyclopropane-1,5'-[5H]inden]-7'(6'H)-one,2',3'-dihydro-3',6'-dihydroxy-2'-(hydroxymethyl)-2',4',6'-trimethyl-, [2'S-(2'a,3'b,6'a)]-; Illudin; Illudine S; Lampterol; Lunamycin; NSC 400979; NSC 626369

Article Data 1

Lunamycin Chemical Properties

Molecular Structure of Lunamycin (CAS NO.64789-67-9):

IUPAC Name: (1R,2S,5R)-1,5-dihydroxy-2-(hydroxymethyl)-2,5,7-trimethylspiro[1H-indene-6,1'-cyclopropane]-4-one
Formula: C15H20O
Molecular Weight: 264.3169 
Surface Tension: 60.2 dyne/cm 
Density: 1.34 g/cm
Flash Point: 276.1 °C 
Enthalpy of Vaporization: 89.82 kJ/mol 
Boiling Point: 509.6 °C at 760 mmHg 
Vapour Pressure: 1.61E-12 mmHg at 25°C 
Index of Refraction: 1.619 
Classification Code : Antibiotics, antineoplastic ; Antineoplastic Agents ; Drug / Therapeutic Agent ; Mutation data ; Natural Product
Synonyms of Lunamycin (CAS NO.64789-67-9): illudin S ; (2'S,3'R,6'R)-2',3'-Dihydro-3',6'-dihydroxy-2'-hydroxymethyl-2',4',6'-trimethylspiro[cyclopropane-1,5'-[5H]inden]-7'(6'H)-one ; Illusin S;Lampterol ; NSC-626369 ; Lampterol ; Lunamycin

Lunamycin Toxicity Data With Reference

1.    

pic-esc 200 ng/plate

    CNREA8    Cancer Research. 43 (1983),2819.
2.    

ivn-mus LD50:30 mg/kg

    85GDA2    CRC Handbook of Antibiotic Compounds, Volumes 1-9. 6 (1981),113.

Lunamycin Consensus Reports

Reported in CNREA8 Cancer Research.

Lunamycin Safety Profile

Poison by intravenous route. Mutation data reported. When heated to decomposition it emits acrid smoke and irritating fumes.

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