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Basic Information
CAS No.: 15475-56-6
Name: Methotrexate sodium
Molecular Structure:
Molecular Structure of 15475-56-6 (Methotrexate sodium)
Formula: C20H22 N8 O5 . x Na
Molecular Weight: 498.409
Synonyms: Glutamicacid, N-[p-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-, sodiumsalt, L-(+)- (8CI); L-Glutamic acid,N-[4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-, sodium salt(9CI); Abitrexate; Methotrexate sodium; Methotrexate sodium salt; SodiumL-(+)-methotrexate
EINECS: 239-495-5
Density: g/cm3
Boiling Point: °Cat760mmHg
Flash Point: °C
Appearance: Orange to yellow crystalline powder
Safety: Poison by intraperitoneal route. An experimental teratogen. Experimental reproductive effects. Human mutation data reported. When heated to decomposition it emits very toxic fumes of Na2O and NOx. See also METHOTREXATE.
PSA: 213.37000
LogP: 0.48700
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  • Methotrexate Sodium CAS NO.15475-56-6

  • Casno:

    15475-56-6

    Methotrexate Sodium CAS NO.15475-56-6

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  • Methotrexate sodium

  • Casno:

    15475-56-6

    Methotrexate sodium

    Min.Order: 1 Kilogram

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    Stable supply Superior quality Advanced technology Sufficient stock Legal /safety production Competitive price Appearance:Transparent to light yellow liquid Storage:Store in RT Package:Safe Packaging Application:api Transportation:By sea

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Chemistry

Product Name: Methotrexate sodium (CAS NO.15475-56-6)


Molecular Formula: C20H21N8NaO5
Molecular Weight: 476.48g/mol
Mol File: 15475-56-6.mol
Einecs: 239-495-5
Appearance: Orange to yellow crystalline powder
H-Bond Donor: 4
H-Bond Acceptor: 12

Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 27mg/kg (27mg/kg)   Polish Journal of Pharmacology and Pharmacy. Vol. 25, Pg. 327, 1973.
mouse LD50 unreported 380mg/kg (380mg/kg)   Cancer Treatment Reports. Vol. 66, Pg. 351, 1982.

Safety Profile

Poison by intraperitoneal route. An experimental teratogen. Experimental reproductive effects. Human mutation data reported. When heated to decomposition it emits very toxic fumes of Na2O and NOx. See also METHOTREXATE.

Specification

 Methotrexate sodium ,its CAS NO. is 15475-56-6,the synonyms is Methotrexate sodium for injection ; Mtx sodium ; n-[4-[[(2,4-Diaminopteridin-6-yl)methyl]methylamino]benzoyl]-l-glutamic acid hydrogen 1-sodium salt ; n-[4-[[(2,4-Diaminopteridine-6-yl)methyl]methylamino]benzoyl]-l-glutamic acid/sodium,(1:x) salt .