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Mequitazine

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Name

Mequitazine

EINECS 249-521-7
CAS No. 29216-28-2 Density 1.28 g/cm3
Solubility Melting Point 143-145 °C
Formula C20H22N2S Boiling Point 469.4 °C at 760 mmHg
Molecular Weight 322.50 Flash Point 237.7 °C
Transport Information Appearance White solid
Safety Risk Codes
Molecular Structure Molecular Structure of 29216-28-2 (10H-Phenothiazine,10-(1-azabicyclo[2.2.2]oct-3-ylmethyl)-) Hazard Symbols
Synonyms

LM 209;Metaplexan;Mircol;NSC 303612;Nipolazin;Primalan;Quitadrill;Zesulan;Phenothiazine,10-(3-quinuclidinylmethyl)- (8CI);Butix;

 

Mequitazine Chemical Properties

Chemical Name: Mequitazine
IUPAC NAME: 10-(1-Azabicyclo[2.2.2]octan-8-ylmethyl)phenothiazine
CAS No.: 29216-28-2
EINECS: 249-521-7
Molecular Formula: C20H22N2S
Molecular Weight: 322.47 g/mol
Melting Point: 143-145°C
Density: 1.28 g/cm3 
Flash Point: 237.7 °C
Boiling Point: 469.4 °C at 760 mmHg
Following is the structure of Mequitazine (29216-28-2):


Product Categories about Mequitazine (29216-28-2) are Heterocyclic Compounds ; Heterocycles ; Intermediates & Fine Chemicals ; Pharmaceuticals
The chemical synonymous of Mequitazine (29216-28-2) are 10-(1-Azabicyclo[2.2.2]oct-3-ylmethyl)-10H-phenothiazine ; 10-(3-Quinuclidinylmethyl)phenothiazine ; Butix ; Instotal ; Lm 209 ; Mequitazina ; Metaplexan ; Mircol

Mequitazine Uses

 Mequitazine (29216-28-2) is used as an antihistamine.

Mequitazine Toxicity Data With Reference

1.    

orl-rat LD50:245 mg/kg

    OYYAA2    Oyo Yakuri. Pharmacometrics. 22 (1981),491.
2.    

ipr-rat LD50:54 mg/kg

    OYYAA2    Oyo Yakuri. Pharmacometrics. 22 (1981),491.
3.    

scu-rat LD50:690 mg/kg

    OYYAA2    Oyo Yakuri. Pharmacometrics. 22 (1981),491.
4.    

orl-mus LD50:210 mg/kg

    OYYAA2    Oyo Yakuri. Pharmacometrics. 22 (1981),491.
5.    

ipr-mus LD50:54 mg/kg

    OYYAA2    Oyo Yakuri. Pharmacometrics. 22 (1981),491.
6.    

scu-mus LD50:278 mg/kg

    OYYAA2    Oyo Yakuri. Pharmacometrics. 22 (1981),491.

Mequitazine Safety Profile

Poison by ingestion, subcutaneous, and intraperitoneal routes. An experimental teratogen. Experimental reproductive effects. An antihistamine. When heated to decomposition it emits toxic fumes of SOx and NOx.

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