Basic Information | Post buying leads | Suppliers | Cas Database |
Name |
N-Acetyl-L-tyrosinamide |
EINECS | 217-756-4 |
CAS No. | 1948-71-6 | Density | 1.253 g/cm3 |
PSA | 92.42000 | LogP | 1.01590 |
Solubility | N/A | Melting Point |
223-225 °C(lit.) |
Formula | C11H14N2O3 | Boiling Point | 459.53 °C at 760 mmHg |
Molecular Weight | 222.244 | Flash Point | 231.716 °C |
Transport Information | N/A | Appearance | white crystalline powder |
Safety | 22-24/25 | Risk Codes | 36/37/38 |
Molecular Structure | Hazard Symbols | Xi | |
Synonyms |
Benzenepropanamide, α-(acetylamino)-4-hydroxy-, (αS)-;Hydrocinnamamide, a-acetamido-p-hydroxy-, L- (8CI);N-Acetyl-4-hydroxy-L-phenylalaninamide;NAYA; |
Article Data | 5 |
Conditions | Yield |
---|---|
With methanol; ammonia |
Conditions | Yield |
---|---|
With ammonia at -40℃; | |
With ammonia |
DL-tryptophanamide radical
A
N-acetyl-L-tryrosinamide
Conditions | Yield |
---|---|
at 20℃; Rate constant; one-electron redox reactions; |
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: acetic acid 2: methanol. NH3 View Scheme |
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: sodium hydroxide / water; 1,4-dioxane / 0 - 20 °C 2: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; dmap; N-ethyl-N,N-diisopropylamine; ammonium chloride / N,N-dimethyl-formamide / 0 - 20 °C View Scheme |
Conditions | Yield |
---|---|
With dmap; ammonium chloride; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 0 - 20℃; |
N-acetyl-L-tryrosinamide
tert-butyldimethylsilyl chloride
N-α-acetyl-O-(tert-butyl(dimethyl)silyl)-L-tyrosinamide
Conditions | Yield |
---|---|
With pyridine; 1H-imidazole for 4h; | 93% |
Conditions | Yield |
---|---|
With calcium hydroxide In water at 20℃; for 1h; | 91% |
N-acetyl-L-tryrosinamide
Conditions | Yield |
---|---|
With dihydrogen peroxide; horseradish peroxidase In various solvent(s) pH=9.4; Enzymatic reaction; | 90% |
N-acetyl-L-tryrosinamide
Conditions | Yield |
---|---|
With palladium(II) trifluoroacetate; dichloroacetonitrile; water In acetonitrile at 60℃; for 5h; Schlenk technique; Inert atmosphere; | 79% |
N-Acetyl-L-tyrosinamide is an organic compound with the formula C11H14N2O3, and its systematic name is the same with the product name. With the CAS registry number 1948-71-6, it is also named as N-Acetyl-4-hydroxy-L-phenylalaninamide. It belongs to the product categories of Amino Acids; Amino Acid Derivatives. Its EINECS number is 217-756-4. In addition, the molecular weight is 222.24. This chemical is stable at common pressure and temperature, and it should be sealed and stored in a cool and dry place. Moreover, it should be protected from strong oxidants. It is used in biochemical research, and it is also uesed in the determination of chymotrypsin substrate.
Physical properties of N-Acetyl-L-tyrosinamide are: (1)ACD/LogP: -1.391; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): -2.64; (4)ACD/LogD (pH 7.4): -1.48; (5)ACD/BCF (pH 5.5): 1.00; (6)ACD/BCF (pH 7.4): 1.00; (7)ACD/KOC (pH 5.5): 1.00; (8)ACD/KOC (pH 7.4): 3.42; (9)#H bond acceptors: 5; (10)#H bond donors: 4; (11)#Freely Rotating Bonds: 5; (12)Polar Surface Area: 92.42 Å2; (13)Index of Refraction: 1.576; (14)Molar Refractivity: 58.73 cm3; (15)Molar Volume: 177.31 cm3; (16)Polarizability: 23.283×10-24cm3; (17)Surface Tension: 54.94 dyne/cm; (18)Density: 1.253 g/cm3; (19)Flash Point: 231.716 °C; (20)Enthalpy of Vaporization: 74.765 kJ/mol; (21)Boiling Point: 459.53 °C at 760 mmHg; (22)Vapour Pressure: 0 mmHg at 25°C.
When you are using this chemical, please be cautious about it as the following:
This chemical is irritating to eyes, respiratory system and skin. You should not breathe dust. When using it, you must avoid contact with skin and eyes.
You can still convert the following datas into molecular structure:
(1)SMILES: Oc1ccc(C[C@H](N)C(=O)NC(C)=O)cc1
(2)Std. InChI: InChI=1S/C11H14N2O3/c1-7(14)13-11(16)10(12)6-8-2-4-9(15)5-3-8/h2-5,10,15H,6,12H2,1H3,(H,13,14,16)/t10-/m0/s1
(3)Std. InChIKey: UECDWMGGNAYEKF-JTQLQIEISA-N