- N-[(10-Oxido-9,10-dihydro-9-oxa-10-phosphaphenanthrene)methyl]-1,3,5-triazine-2,4,6-triamine
- N10-(Trifluoroacetyl)pteroic acid
- N-[1,1'-Biphenyl]-4-yl-9,9-dimethyl-9H-fluoren-2-amine
- N-[1,1'-Biphenyl]-4-yl-9,9-dimethyl-9H-fluoren-3-amine
- N-[1,1'-Biphenyl]-4-yl-N-(4-bromophenyl)-9,9-dimethyl-9H-fluoren-2-amine
- N-[1,1-Bis[(acetyloxy)methyl]-3-(4-octylphenyl)propyl]acetamide
- N'-[(1,1-Dimethylethoxy)carbonyl]-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-N'-methyl-L-lysine
- N1,1-Diphenyl-1,2-ethanediamine
- N-(1,2-Dimethylpropyl)-2-pyridinamine
- 1-(3,4-DIMETHYL-5-ISOXAZOLYL)SULFANIL-AMIDE LITHIUM SALT ">N1-(3,4-DIMETHYL-5-ISOXAZOLYL)SULFANIL-AMIDE LITHIUM SALT
- 4940-39-04H-1-Benzopyran-2-carboxylicacid, 4-oxo-
- 494-04-23,2':4',3''-Terpyridine
- 494-19-95H-Dibenz[b,f]azepine,10,11-dihydro-
- 494210-67-22H-Thiopyran-4-propanoicacid, a-[[(1,1-dimethylethoxy)carbonyl]amino]tetrahydro-
- 4942-47-61-Adamantaneacetic acid
- 4943-67-31H-Pyrrolo[3,2-b]pyridine, 5-methyl-
- 494-38-23,6-Acridinediamine,N3,N3,N6,N6-tetramethyl-
- 4943-86-6Benzamide,2-amino-N-(4-chlorophenyl)-
- 4944-60-91,9-Nonanediol,1,9-diacetate
- 494-52-0Pyridine,3-(2S)-2-piperidinyl-
Hot Products
- 104987-11-3Tacrolimus
- 141-53-7Sodium formate
- 8001-54-5Quaternary ammonium compounds, alkylbenzyldimethyl, chlorides
- 9003-39-8Povidone
- 10161-34-9Trenbolone acetate
- 402957-28-2Telaprevir
- 68-19-9Cyanocobalamin
- 7631-86-9Silicon dioxide
- 302-79-4Tretinoin
- 77-92-9Citric acid
|
Basic Information |
|
Post buying leads |
|
Suppliers |
| Name |
N,N-Bis(2-Chloroethyl)-2-naphthylamine |
EINECS | N/A |
| CAS No. | 494-03-1 | Density | 1.234g/cm3 |
| PSA | 3.24000 | LogP | 4.12380 |
| Solubility | N/A | Melting Point |
54-56° |
| Formula | C14H15Cl2N | Boiling Point | 414.3°C at 760 mmHg |
| Molecular Weight | 268.186 | Flash Point | 204.4°C |
| Transport Information | N/A | Appearance | N/A |
| Safety | Confirmed human carcinogen producing bladder tumors. Human and experimental carcinogenic data. Moderately toxic by intraperitoneal route. When heated to decomposition it emits very toxic fumes of Cl− and NOx. | Risk Codes | N/A |
| Molecular Structure |
|
Hazard Symbols | N/A |
| Synonyms |
2-Naphthalenamine, N,N-bis(2-chloroethyl)-;Chlornaphthin;Chloronaphthine;Aleukon;Chloronaftina;Chloronaphthina;Nafticlorina;Chlornaphazine;Chlornaphazin;Chlornaftina;Cloronaftina; |
N,N-Bis(2-Chloroethyl)-2-naphthylamine Chemical Properties
IUPAC Name: N,N-Bis(2-Chloroethyl)naphthalen-2-amine
Synonyms: b-Naphthylbis(b-chloroethyl)amine ; b-Naphthyldi(2-chloroethyl)amine ; Di(2-Chloroethyl)-.beta.-naphthylamine ; Di(2-Chloroethyl)-b-naphthylamine ; Dichloroethyl-.beta.-naphthylamine
CAS NO: 494-03-1
Molecular Formula of N,N-Bis(2-Chloroethyl)-2-naphthylamine (CAS NO.494-03-1) : C14H15Cl2N
Molecular Weight of N,N-Bis(2-Chloroethyl)-2-naphthylamine (CAS NO.494-03-1) :268.1816
Molecular Structure of N,N-Bis(2-Chloroethyl)-2-naphthylamine (CAS NO.494-03-1) :.jpg)
EINECS: 207-785-0
Index of Refraction: 1.63
Surface Tension: 47.1 dyne/cm
Density: 1.234 g/cm3
Flash Point: 204.4 °C
Enthalpy of Vaporization: 66.72 kJ/mol
Boiling Point: 414.3 °C at 760 mmHg
Vapour Pressure: 4.49E-07 mmHg at 25°C
Melting point: 54 ~ 56 °C.
Appearance:Colorless plates or brown solid.
Solubility: very slightly soluble in water, glycerol, soluble in petroleum ether, ethanol, olive oil, ethyl ether, benzene
N,N-Bis(2-Chloroethyl)-2-naphthylamine Uses
N,N-Bis(2-Chloroethyl)-2-naphthylamine (CAS NO.494-03-1) is used as anti-tumor drug.
N,N-Bis(2-Chloroethyl)-2-naphthylamine Production
N,N-Bis(2-Chloroethyl)-2-naphthylamine (CAS NO.494-03-1) is obtained from 2 - Amino-naphthalene as a raw material .
N,N-Bis(2-Chloroethyl)-2-naphthylamine Toxicity Data With Reference
| 1. | mmo-sat 40 µg/plate | CNREA8 Cancer Research. 37 (1977),2209. | ||
| 2. | mma-sat 10 µg/plate | PNASA6 Proceedings of the National Academy of Sciences of the United States of America. 72 (1975),5135. | ||
| 3. | dnd-dmg-orl 260 µmol/L | CNREA8 Cancer Research. 30 (1970),195. | ||
| 4. | ipr-rat LD50:1086 mg/kg | BCPCA6 Biochemical Pharmacology. 13 (1964),969. |
N,N-Bis(2-Chloroethyl)-2-naphthylamine Consensus Reports
IARC Cancer Review: Group 1 IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man 7 (1987),p. 130.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Animal Sufficient Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man 4 (1974),p. 119.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Human Sufficient Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man 4 (1974),p. 119.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) . EPA Genetic Toxicology Program.
N,N-Bis(2-Chloroethyl)-2-naphthylamine Safety Profile
Confirmed human carcinogen producing bladder tumors. Human and experimental carcinogenic data. Moderately toxic by intraperitoneal route. When heated to decomposition it emits very toxic fumes of Cl− and NOx.
N,N-Bis(2-Chloroethyl)-2-naphthylamine Specification
1.Air & Water Reactions :Insoluble in water.
2.Reactivity Profile :chlornaphazine reacts with nucleophiles .
3.Fire Hazard: Flash point data are not available for chlornaphazine , but chlornaphazine is probably combustible.
What can I do for you?
Get Best Price
