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N,N-Dimethylsalicylamide

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Name

N,N-Dimethylsalicylamide

EINECS N/A
CAS No. 1778-08-1 Density 1.153g/cm3
PSA 40.54000 LogP 1.09400
Solubility N/A Melting Point N/A
Formula C9H11 N O2 Boiling Point 314.9°Cat760mmHg
Molecular Weight 165.192 Flash Point 144.3°C
Transport Information N/A Appearance N/A
Safety Moderately toxic by ingestion and intraperitoneal routes. When heated to decomposition it emits toxic fumes of NOx. Risk Codes 22-36
Molecular Structure Molecular Structure of 1778-08-1 (2-Hydroxy-N,N-dimethyl-benzamide) Hazard Symbols Xn
Synonyms

Salicylamide,N,N-dimethyl- (6CI,7CI,8CI); 2-Hydroxy-N,N-dimethylbenzamide;N,N-Dimethyl-2-hydroxybenzamide; N,N-Dimethylsalicylamide; NSC 212254;o-Hydroxy-N,N-dimethylbenzamide

Article Data 17

N,N-Dimethylsalicylamide Chemical Properties

Product Name: N,N-Dimethylsalicylamide (CAS NO.1778-08-1)


Molecular Formula: C9H11NO2
Molecular Weight: 165.18914g/mol
Mol File: 1778-08-1.mol
Boiling point: 314.9 °C at 760 mmHg
Flash Point: 144.3 °C
Density: 1.153 g/cm3
Surface Tension: 46 dyne/cm
Enthalpy of Vaporization: 57.83 kJ/mol
Vapour Pressure: 0.000244 mmHg at 25°C
XLogP3-AA: 0.4
H-Bond Donor: 1
H-Bond Acceptor: 2
Structure Descriptors of N,N-Dimethylsalicylamide (CAS NO.1778-08-1):
  IUPAC Name: 2-hydroxy-N,N-dimethylbenzamide
  Canonical SMILES: CN(C)C(=O)C1=CC=CC=C1O
  InChI: InChI=1S/C9H11NO2/c1-10(2)9(12)7-5-3-4-6-8(7)11/h3-6,11H,1-2H3 
  InChIKey: UBAYZMJYXBTDBB-UHFFFAOYSA-N

N,N-Dimethylsalicylamide Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 1100mg/kg (1100mg/kg)   Yakugaku Zasshi. Journal of Pharmacy. Vol. 86, Pg. 120, 1966.
rat LD50 intraperitoneal 2gm/kg (2000mg/kg)   Journal of Pharmacology and Experimental Therapeutics. Vol. 108, Pg. 450, 1953.
rat LD50 oral 2300mg/kg (2300mg/kg)   Journal of Pharmacology and Experimental Therapeutics. Vol. 108, Pg. 450, 1953.

N,N-Dimethylsalicylamide Safety Profile

Moderately toxic by ingestion and intraperitoneal routes. When heated to decomposition it emits toxic fumes of NOx.

N,N-Dimethylsalicylamide Specification

 N,N-Dimethylsalicylamide ,its CAS NO. is 1778-08-1,the synonyms is  4-10-00-00170 (Beilstein Handbook Reference) ; BRN 2361721  ; NSC 212254 ; Salicyldimethylamide ; Benzamide, 2-hydroxy-N,N-dimethyl- (9CI) ; Salicylamide, N,N-dimethyl- .

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