2-hydroxy-N,N-dimethylbenzamide

Base Information

Chemical Name:2-hydroxy-N,N-dimethylbenzamide
CAS No.:1778-08-1
Molecular Formula:C9H11 N O2
Molecular Weight:165.192
Hs Code.:2924299090
European Community (EC) Number:827-939-6
NSC Number:212254
UNII:W67JMY7PNV
DSSTox Substance ID:DTXSID70170380
Nikkaji Number:J48.301J
Wikidata:Q83040299
Mol file:1778-08-1.mol

Synonyms:2-hydroxy-N,N-dimethylbenzamide;1778-08-1;N,N-Dimethylsalicylamide;Salicyldimethylamide;Salicylamide, N,N-dimethyl-;Benzamide, 2-hydroxy-N,N-dimethyl-;2-hydroxy-N,N-dimethyl-benzamide;NSC 212254;BRN 2361721;MFCD00456946;NSC-212254;Salicylamide Me;NSC212254;Salicylamide,N-dimethyl-;W67JMY7PNV;WLN: QR BVN1&1;F3308-0299;SCHEMBL1446966;n,n-dimethyl-2-hydroxybenzamide;o-Hydroxy-N,N-dimethylbenzamide;DTXSID70170380;2-hydroxybenzoic acid dimethylamide;Hydroxyphenylcarbonsauredimethylamide;BAA77808;AKOS000212183;MB01180;BS-35796;LS-144155;2-Hydroxy-N,N-dimethylbenzamide, AldrichCPR;CS-0141020;FT-0709213;EN300-102097;Z68247186

Suppliers and Price of 2-hydroxy-N,N-dimethylbenzamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-Hydroxy-N,N-dimethylbenzamide
100mg
$ 65.00

Sigma-Aldrich
2-Hydroxy-N,N-dimethylbenzamide Aldrich
1g
$ 99.60

Crysdot
2-Hydroxy-N,N-dimethylbenzamide 95+%
5g
$ 446.00

Crysdot
2-Hydroxy-N,N-dimethylbenzamide 95+%
25g
$ 1330.00

ChemBridge Corporation
2-hydroxy-N,N-dimethylbenzamide 95%
5 g
$ 205.00

ChemBridge Corporation
2-hydroxy-N,N-dimethylbenzamide 95%
1 g
$ 70.00

American Custom Chemicals Corporation
2-HYDROXY-N,N-DIMETHYLBENZAMIDE 95.00%
5G
$ 1421.65

American Custom Chemicals Corporation
2-HYDROXY-N,N-DIMETHYLBENZAMIDE 95.00%
2.5G
$ 1147.43

AK Scientific
2-Hydroxy-N,N-dimethylbenzamide
5g
$ 650.00

AK Scientific
2-Hydroxy-N,N-dimethylbenzamide
2.5g
$ 432.00

Total 11 raw suppliers

Chemical Property of 2-hydroxy-N,N-dimethylbenzamide

Chemical Property:

Vapor Pressure:0.000244mmHg at 25°C
Refractive Index:1.5270 (estimate)
Boiling Point:314.9°Cat760mmHg
Flash Point:144.3°C
PSA：40.54000
Density:1.153g/cm³
LogP:1.09400
XLogP3:0.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:165.078978594
Heavy Atom Count:12
Complexity:168

Purity/Quality:

99% ^*data from raw suppliers

2-Hydroxy-N,N-dimethylbenzamide ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xn
Hazard Codes:Xn
Statements: 22-36
Safety Statements: 26

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN(C)C(=O)C1=CC=CC=C1O

Technology Process of 2-hydroxy-N,N-dimethylbenzamide

There total 29 articles about 2-hydroxy-N,N-dimethylbenzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 6969-90-0
phenyl N,N-dimethylcarbamate

: 1778-08-1
2-hydroxy-N,N-dimethylbenzamide

Guidance literature:: With lithium diisopropylamide; In tetrahydrofuran;
DOI:10.1021/acs.joc.9b00968

Reference yield: 84.0%

: 124-40-3
dimethyl amine

: 69-72-7,25496-36-0,8052-31-1
salicylic acid

: 1778-08-1
2-hydroxy-N,N-dimethylbenzamide

Guidance literature:: salicylic acid; With 1,1'-carbonyldiimidazole; In tetrahydrofuran; at 70 ℃; for 20h;

dimethyl amine; In tetrahydrofuran; at 70 ℃; for 20h;

Reference yield: 84.0%

: 611-74-5
N,N-dimethylbenzamide

: 1778-08-1
2-hydroxy-N,N-dimethylbenzamide

Guidance literature:: N,N-dimethylbenzamide; With dirhodium tetraacetate; triethylamine triflouroacetate; trifluoroacetic acid; trifluoroacetic anhydride; at 20 ℃; Electrolysis; Inert atmosphere; Schlenk technique;

With water; sodium hydrogencarbonate; Inert atmosphere; Schlenk technique;
DOI:10.1002/anie.202017359