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NEROL

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Name

NEROL

EINECS 203-378-7
CAS No. 106-25-2 Density 0.866 g/cm3
PSA 20.23000 LogP 2.67140
Solubility 1.311g/L(25 oC) Melting Point < -10oC
Formula C10H18O Boiling Point 229.5 °C at 760 mmHg
Molecular Weight 154.252 Flash Point 76.7 °C
Transport Information N/A Appearance Clear colorless to almost colorless liquid
Safety 26-36 Risk Codes 36/37/38
Molecular Structure Molecular Structure of 106-25-2 (2,6-Octadien-1-ol,3,7-dimethyl-, (2Z)-) Hazard Symbols IrritantXi
Synonyms

cis-Geraniol;b-Nerol;2,6-Octadien-1-ol,3,7-dimethyl-, (Z)- (8CI);Nerol (6CI);(2Z)-3,7-Dimethyl-2,6-octadien-1-ol;(Z)-3,7-Dimethyl-2,6-octadien-1-ol;(Z)-Geraniol;(Z)-Nerol;2-cis-3,7-Dimethyl-2,6-octadien-1-ol;3,7-Dimethyl-cis-2,6-octadien-1-ol;Nerol900;Neryl alcohol;cis-3,7-Dimethyl-2,6-octadien-1-ol;

Article Data 188

NEROL Synthetic route

Carbonic acid allyl ester (Z)-3,7-dimethyl-octa-2,6-dienyl ester

Conditions
ConditionsYield
With palladium diacetate; sodium azide; trisodium tris(3-sulfophenyl)phosphine In water; acetonitrile at 25℃; for 1h;98%
5392-40-5

(E/Z)-3,7-dimethyl-2,6-octadienal

Conditions
ConditionsYield
With isopropyl alcohol; zirconium(IV) oxide for 6h; Rate constant; Heating;97%
With isopropyl alcohol; zirconium(IV) oxide for 6h; Heating;97%
With sodium formate; RuCl2(m-SPPh2)2 In water at 80℃; for 7h;95%
80873-76-3

1-(tert-butyldimethylsiloxy)-3,7-dimethyl-2,6-octadiene

Conditions
ConditionsYield
With acetonyltriphenylphosphonium bromide In methanol; dichloromethane at 20℃; for 0.0833333h;95%
In methanol; dichloromethane for 3.66667h; Irradiation;
In methanol; dichloromethane for 3.66667h; Product distribution; Irradiation; other silyl ethers; phenanthrene, var. time;

2-((Z)-3,7-Dimethyl-octa-2,6-dienyloxymethyl)-1,3-dimethyl-benzene

Conditions
ConditionsYield
With lithium; ethylenediamine In tetrahydrofuran at -10℃; for 2h;93%
52537-25-4

(Z)-1-(allyloxy)-3,7-dimethylocta-2,6-diene

Conditions
ConditionsYield
With samarium diiodide; water; isopropylamine In tetrahydrofuran at 20℃; for 0.0333333h;88%
106-26-3

cis-3,7-dimethyl-2,6-octadienal

Conditions
ConditionsYield
With indium tri-isopropoxide supported on mesoporous SBA-15 In isopropyl alcohol at 80℃; for 7h; Reagent/catalyst; Meerwein-Ponndorf-Verley Reduction; Inert atmosphere; Schlenk technique; chemoselective reaction;87.6%
With potassium hydroxide; isopropyl alcohol; dichlorotetrakis(dimethylsulfoxide)ruthenium at 20℃; for 3h;86.8%
With Triisopropyl borate; isopropyl alcohol at 27℃; for 20h; Kinetics; Reagent/catalyst; Meerwein-Ponndorf-Verley reduction; Inert atmosphere; chemoselective reaction;83.1%
70473-31-3

neryl 2-tetrahydropyranyl ether

Conditions
ConditionsYield
ammonium cerium(IV) nitrate In alkaline aq. solution; acetonitrile at 70℃; for 2h; pH=8; Decomposition;86%
With tin(ll) chloride In methanol Substitution;80%
With boron trifluoride diethyl etherate; dimethylthio-dimethyl-tin In toluene at -20 - 0℃; for 12h;82 % Chromat.
13058-12-3

ethyl 3,7-dimethyl-2,6-octadienoate

Conditions
ConditionsYield
With lithium aluminium tetrahydride81%
With diisobutylaluminium hydride In diethyl ether; hexane at -78 - 20℃; for 12.5h;0.9 g
74323-42-5

morpholide of 1-hydroxy-3,7-dimethylocta-2Z,6-diene-4-sulfonic acid

A

106-25-2

Nerol

B

16750-94-0

2,6-dimethyl-2,5-octadien-8-ol

Conditions
ConditionsYield
With dibenzo-18-crown-6; sodium In tetrahydrofuran; benzene-d6 at -70℃; for 0.0333333h;A 75%
B 4%
With dibenzo-18-crown-6; sodium In ammonia at -70℃; for 2h;A 75%
B 4%
With sodium; tert-butyl alcohol In benzene-d6 at -70℃; Yield given. Yields of byproduct given;
With lithium; tert-butyl alcohol In ammonia at -70℃; Product distribution; also Na, (DB18C6) or Na, tBuOH in NH3;
With lithium In diethyl ether; ammonia at -65℃; Product distribution; other reagent, solvent, temperature;
141-12-8

neryl acetate

Conditions
ConditionsYield
With tris(2,4,6-trimethoxyphenyl)phosphine In methanol at 50℃; for 24h;73%

NEROL Chemical Properties

MF: C10H18O
Synonyms: (2Z)-3,7-Dimethyl-2,6-octadien-1-ol;(Z)-Geraniol;2,6-Octadien-1-ol,3,7-dimethyl-,(Z)-;2-cis-3,7-Dimethyl-2,6-octadien-1-ol;3,7-dimethyl-octa-2cis,6-dien-1-ol;6-Octadien-1-ol,3,7-dimethyl-,(Z)-2;7-dimethyl-6-octadien-1-o(z)-3;beta-nerol
MW: 154.25
EINECS: 203-378-7
bp : 103-105 °C9 mm Hg(lit.)
density : 0.876 g/mL at 25 °C(lit.)
refractive index : n20/D 1.474(lit.)
FEMA : 2770
Fp : 226 °F
Merck : 14,6475
BRN : 1722455

NEROL Uses

NEROL is used in perfumery.

NEROL Safety Profile

Hazard Codes : Xi
Risk Statements : 36/37/38
Safety Statements : 26-36
WGK Germany : 2
RTECS : RG5840000
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