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| CAS No.: | 73986-53-5 |
|---|---|
| Name: | O-DEMETHLY TRAMADOL |
| Molecular Structure: | |
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| Formula: | C15H23NO2 |
| Molecular Weight: | 249.353 |
| Synonyms: | O-Desmethyltramadol; |
| Density: | 1.104 g/cm3 |
| Boiling Point: | 403.3 °C at 760 mmHg |
| Flash Point: | 201.2 °C |
| PSA: | 43.70000 |
| LogP: | 2.33160 |
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[2-(2,6-dichloroanilino)phenyl]acetic acid
- 73986-53-5
O-desmethyltramadol
| Conditions | Yield |
|---|---|
| In isopropyl alcohol at 20℃; Product distribution / selectivity; | 100% |
| Conditions | Yield |
|---|---|
| In toluene at 20℃; for 3h; | 91% |
- 67127-78-0
3-acetyl-2-hydroxybenzoic acid
- 73986-53-5
O-desmethyltramadol
| Conditions | Yield |
|---|---|
| In chloroform at 20℃; Product distribution / selectivity; | 88% |
| Conditions | Yield |
|---|---|
| In ethyl acetate at 0 - 20℃; for 0.666667h; Product distribution / selectivity; Cooling with ice; | 77% |
- 73986-53-5
O-desmethyltramadol
- 22204-53-1
(2S)-2-(6-methoxy(2-naphthyl))propanoic acid
| Conditions | Yield |
|---|---|
| In chloroform Product distribution / selectivity; Heating; | 66% |
| Conditions | Yield |
|---|---|
| In acetic acid butyl ester Product distribution / selectivity; | 65% |
- 227626-60-0
N-Boc-gabapentin
- 73986-53-5
O-desmethyltramadol
- 1345016-64-9
(1R2R,1S2S)-3-(2-((dimethylamino)methyl)-1-hydroxycyclohexyl)phenyl 2-(1-((tert-butoxycarbonylamino)methyl)cyclohexyl)acetate
| Conditions | Yield |
|---|---|
| With dmap; dicyclohexyl-carbodiimide In dichloromethane; N,N-dimethyl-formamide at 20℃; for 16h; | 44% |
- 64269-79-0
Carbonyldiimidazole
- 15687-27-1
ibuprofen
- 73986-53-5
O-desmethyltramadol
- 269079-66-5
3-(2-dimethylaminomethyl-1-hydroxy-cyclohexyl)-phenyl 2-(4-isobutyl-phenyl)-propionate
| Conditions | Yield |
|---|---|
| With sodium hydroxide In tetrahydrofuran; dichloromethane; water; mineral oil | |
| With sodium hydroxide In tetrahydrofuran; dichloromethane; water; mineral oil |
This product is a nationally controlled contraband, and the Lookchem platform doesn't provide relevant sales information.
Specification
The O-Desmethyltramadol is an organic compound with the formula C15H23NO2. The IUPAC name of this chemical is 3-[2-(dimethylaminomethyl)-1-hydroxycyclohexyl]phenol. With the CAS registry number 73986-53-5, it is also named as phenol, 3-[2-[(dimethylamino)methyl]-1-hydroxycyclohexyl]-.
Physical properties about O-Desmethyltramadol are: (1)ACD/LogP: 1.779; (2)ACD/LogD (pH 5.5): -1.26; (3)ACD/LogD (pH 7.4): -0.25; (4)ACD/BCF (pH 5.5): 1.00; (5)ACD/BCF (pH 7.4): 1.00; (6)ACD/KOC (pH 5.5): 1.00; (7)ACD/KOC (pH 7.4): 2.09; (8)#H bond acceptors: 3; (9)#H bond donors: 2; (10)#Freely Rotating Bonds: 5; (11)Index of Refraction: 1.561; (12)Molar Refractivity: 73.173 cm3; (13)Molar Volume: 225.818 cm3; (14)Polarizability: 29.008 10-24cm3; (15)Surface Tension: 46.390998840332 dyne/cm; (16)Density: 1.104 g/cm3; (17)Flash Point: 201.156 °C; (18)Enthalpy of Vaporization: 69.031 kJ/mol; (19)Boiling Point: 403.338 °C at 760 mmHg
You can still convert the following datas into molecular structure:
(1)InChI=1S/C15H23NO2/c1-16(2)11-13-6-3-4-9-15(13,18)12-7-5-8-14(17)10-12/h5,7-8,10,13,17-18H,3-4,6,9,11H2,1-2H3;
(2)InChIKey=UWJUQVWARXYRCG-UHFFFAOYSA-N;
(3)SmilesCN(C)CC1CCCCC1(c2cccc(c2)O)O;
The toxicity data is as follows:
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| mouse | LD50 | oral | 387mg/kg (387mg/kg) | BEHAVIORAL: ANALGESIA | Arzneimittel-Forschung. Drug Research. Vol. 28, Pg. 107, 1978. |