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Name	O-Phthalimide	EINECS	201-603-3
CAS No.	85-41-6	Density	1.367 g/cm³
PSA	46.17000	LogP	0.89900
Solubility	<0.1 g/100 mL at 19.5 °C in water	Melting Point	232-235 °C(lit.)
Formula	C₈H₅NO₂	Boiling Point	359 °C at 760 mmHg
Molecular Weight	147.133	Flash Point	170.9 °C
Transport Information	N/A	Appearance	white to slightly yellowish crystalline flakes
Safety	22-24/25	Risk Codes	20/21/22-36/37/38-40
Molecular Structure		Hazard Symbols	N/A
Synonyms	1H-Isoindole-1,3(2H)-dione;1,2-Benzenedicarboximide;1,3-Dihydro-2H-isoindole-1,3-dione;1,3-Dioxo-1,3-dihydroisoindole;1,3-Isoindolinedione;Benzoimide;Isoindole-1,3-dione;Kladnoite;Levegal PEW-T;NSC 3108;Phthalicdicarboximide;Phthalimide;

O-Phthalimide Chemical Properties

IUPAC Name: Isoindole-1,3-dione
Synonyms of Phthalimide (CAS NO.85-41-6): 1,2-Benzenedicarboximide ; 1,3-Isoindolinedione ; 1H-Isoindole-1,3(2H)-dione ; 2-Diazoindan-1,3-dione ; 5-21-10-00270 (Beilstein Handbook Reference) ; AI3-07565 ; BRN 0118522 ; Benzoimide ; EINECS 201-603-3 ; Ftalimmide ; Ftalimmide [Italian] ; HSDB 5007 ; Isoindole-1,3-dione ; NSC 3108 ; Phthalimid ; Phthalimid [German] ; Phthalimide ; o-Phthalic imide
CAS NO: 85-41-6
Classification Code: Reproductive Effect
Molecular Formula: C₈H₅NO₂
Molecular Weight: 147.1308
Molecular Structure:

Melting Point: 232-235 °C
Polar Surface Area: 37.38 Å²
Index of Refraction: 1.612
Molar Refractivity: 37.42 cm³
Molar Volume: 107.5 cm³
Surface Tension: 53.6 dyne/cm
Density: 1.367 g/cm³
Flash Point: 170.9 °C
Enthalpy of Vaporization: 63.79 kJ/mol
Boiling Point: 359 °C at 760 mmHg V
apour Pressure: 8.84E-06 mmHg at 25°C

O-Phthalimide Uses

Phthalimide (CAS NO.85-41-6) is widely used in plastics,chemical synthesis, and researches.It's used in the production of pesticides, dyes, spices, pharmaceuticals, rubber chemicals CTP,and it could also be used in the production of high-performance ion-exchange resins, surfactants,etc.

O-Phthalimide Toxicity Data With Reference

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
mouse	LD50	intraperitoneal	1175mg/kg (1175mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD	Medicina Experimentalis. Vol. 11, Pg. 149, 1964.
mouse	LD50	oral	5gm/kg (5000mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)	Farmaco, Edizione Scientifica. Vol. 20, Pg. 3, 1965.
rat	LD	intraperitoneal	> 500mg/kg (500mg/kg)		National Academy of Sciences, National Research Council, Chemical-Biological Coordination Center, Review. Vol. 5, Pg. 23, 1953.

O-Phthalimide Consensus Reports

Reported in EPA TSCA Inventory.

O-Phthalimide Safety Profile

Moderately toxic by intraperitoneal route. Mildly toxic by ingestion. An experimental teratogen. Other experimental reproductive effects. When heated to decomposition it emits toxic fumes of NO_x.
The Risk Statements information of Phthalimide (CAS NO.85-41-6) :
40: Limited evidence of a carcinogenic effect
20/21/22: Harmful by inhalation, in contact with skin and if swallowed
36/37/38: Irritating to eyes, respiratory system and skin
The Safety Statements information of Phthalimide (CAS NO.85-41-6):
22: Do not breathe dust
24/25: Avoid contact with skin and eyes
WGK Germany: 1

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