Basic Information | Post buying leads | Suppliers |
Name |
Oleandomycin phosphate |
EINECS | N/A |
CAS No. | 7060-74-4 | Density | N/A |
PSA | 253.55000 | LogP | 0.97990 |
Solubility | N/A | Melting Point |
145-147℃ |
Formula | C35H61NO12•H3O4P | Boiling Point | N/A |
Molecular Weight | 785.97 | Flash Point | N/A |
Transport Information | N/A | Appearance | N/A |
Safety | Poison by intravenous route. Moderately toxic by ingestion and subcutaneous routes. When heated to decomposition it emits toxic fumes of POx and NOx. See also PHOSPHATES. | Risk Codes | N/A |
Molecular Structure | Hazard Symbols | N/A | |
Synonyms |
OleandomycinPhosphate |
oleandomycin phosphate
8-methylene-oleandomycin
Conditions | Yield |
---|---|
With chromium dichloride In water; acetone at 20℃; for 0.75h; |
IUPAC Name: (3S,5S,6S,7R,8S,9R,12R,13R,14S,15R)-6-[(2S,3R,4S,6R)-4-Dimethylamino-3-hydroxy-6-methyl-tetrahydropyran-2-yl]oxy-14-hydroxy-8-[(2R,4S,5S,6S)-5-hydroxy-4-methoxy-6-methyl-tetrahydropyran-2-yl]oxy-5,7,9,12,13,15-hexamethyl-1,11-dioxaspiro[2.13]hexadecane-10,16-dione; phosphoric acid
Synonyms: (3S,5R,6S,7R,8R,11R,12S,13R,14S,15S)-6-Hydroxy-5,7,8,11,13,15-hexamethyl-4,10-dioxo-14-{[3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranosyl]oxy}-1,9-dioxaspiro[2.13]hexadec-12-yl 2,6-dideoxy-3-O-methyl-alpha-L-arabino-hexopyranoside phosphate (1:1) ; 1,9-Dioxaspiro[2.13]hexadecane-4,10-dione, 12-[(2,6-dideoxy-3-O-methyl-alpha-L-arabino-hexopyranosyl)oxy]-6-hydroxy-5,7,8,11,13,15-hexamethyl-14-[[3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranosyl]oxy]-, (3S,5R,6S,7R,8R,11R,12S,13R,14S,15S)-, phosphate (1:1) (salt) ; Matromycin (phosphate) ; Oleandomycin phosphate (JAN)
CAS NO:7060-74-4
Molecular Formula of Oleandomycin phosphate (CAS NO.7060-74-4) :C35H64NO16P
Molecular Weight of Oleandomycin phosphate (CAS NO.7060-74-4) :785.85
Molecular Structure of Oleandomycin phosphate (CAS NO.7060-74-4) :
EINECS: 230-351-7
Flash Point: 518 °C
Enthalpy of Vaporization: 153.99 kJ/mol
Boiling Point: 932.9 °C at 760 mmHg
Vapour Pressure: 0 mmHg at 25°C
Storage temp: 0-6°C
Oleandomycin phosphate (CAS NO.7060-74-4) is effective against staphylococci, streptococci, pneumococci, and some Gram-negative bacteria.
Oleandomycin phosphate (CAS NO.7060-74-4) is an antibiotic substance produced by species of Streptomyces .antibioticus.
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
mouse | LD50 | intravenous | 400mg/kg (400mg/kg) | Drugs in Japan Vol. 6, Pg. 164, 1982. | |
mouse | LD50 | oral | 4gm/kg (4000mg/kg) | Drugs in Japan Vol. 6, Pg. 164, 1982. | |
mouse | LD50 | subcutaneous | 1gm/kg (1000mg/kg) | Drugs in Japan Vol. 6, Pg. 164, 1982. | |
rat | LD50 | intravenous | 480mg/kg (480mg/kg) | BEHAVIORAL: ATAXIA BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION | Antibiotics and Chemotherapy Vol. 7, Pg. 419, 1957. |
Poison by intravenous route. Moderately toxic by ingestion and subcutaneous routes. When heated to decomposition it emits toxic fumes of POx and NOx. See also PHOSPHATES.
Safety Statements 22-24/25
S22:Do not breathe dust.
S24/25:Avoid contact with skin and eyes.
RIDADR UN2811 6.1/PG 2
RTECS RJ9800000