In 1966,Oxcarbazepine(28721-07-5): was first synthesized, and it wasapproved for use as an anticonvulsant in Denmark in 1990. It was approved in Spain in 1993, in Portugal in 1997, and eventually for all other EU countries in 1999. It was approved in the US in 2000.

1. Introduction of Oxcarbazepine
Oxcarbazepine is one kind of yellow to pale yellow crystalline powder. The IUPAC name of this chemical is 5-oxo-6H-benzo[b][1]benzazepine-11-carboxamide. With the CAS registry number 28721-07-5, it is also named as 10-Oxo-10,11-dihydro-5H-dibenzo[b,f]azepin-5-carboxamid. The product's categories are Heterocyclic Compounds; APIs; Intermediates & Fine Chemicals; Pharmaceuticals. Besides, the Classification Code of this chemical is Anticonvulsant; Anticonvulsants; Antiepileptic; Central Nervous System Agents; Reproductive Effect. Oxcarbazepine is a poorly water-soluble.

2. Properties of Oxcarbazepine
Physical properties about Oxcarbazepine are:
(1)ACD/LogP: 1.44; (2)ACD/LogD (pH 5.5): 1.44; (3)ACD/LogD (pH 7.4): 1.44; (4)ACD/BCF (pH 5.5): 7.27; (5)ACD/BCF (pH 7.4): 7.27; (6)ACD/KOC (pH 5.5): 143.92; (7)ACD/KOC (pH 7.4): 143.92; (8)#H bond acceptors: 4; (9)#H bond donors: 2; (10)Polar Surface Area: 40.62 Å²; (11)Index of Refraction: 1.661; (12)Molar Refractivity: 70.21 cm³; (13)Molar Volume: 189.7 cm³; (14)Polarizability: 27.83×10^-24cm³; (15)Surface Tension: 61.2 dyne/cm; (16)Density: 1.329 g/cm³; (17)Flash Point: 230.3 °C; (18)Enthalpy of Vaporization: 71.73 kJ/mol; (19)Boiling Point: 457.2 °C at 760 mmHg; (20)Vapour Pressure: 1.52E-08 mmHg at 25°C.

3. Structure Descriptors of Oxcarbazepine
You can still convert the following datas into molecular structure:
(1)SMILES: O=C3c1c(cccc1)N(c2ccccc2C3)C(=O)N
(2)InChI: InChI=1/C15H12N2O2/c16-15(19)17-12-7-3-1-5-10(12)9-14(18)11-6-2-4-8-13(11)17/h1-8H,9H2,(H2,16,19)
(3)InChIKey: CTRLABGOLIVAIY-UHFFFAOYAH
(4)Std. InChI: InChI=1S/C15H12N2O2/c16-15(19)17-12-7-3-1-5-10(12)9-14(18)11-6-2-4-8-13(11)17/h1-8H,9H2,(H2,16,19)
(5)Std. InChIKey: CTRLABGOLIVAIY-UHFFFAOYSA-N

4. Physical Properties of Oxcarbazepine

6. Safety Information of Oxcarbazepine
WGK Germany: 3
RTECS: HN8445000

7. Uses of Oxcarbazepine
The Oxcarbazepine is an organic compound with the formula C₁₅H₁₂N₂O₂. Besides, it is a pale yellow powder, which is an anticonvulsant and mood stabilizing drug, used primarily in the treatment of epilepsy and bipolar disorder, and also used to treat anxiety disorders. Besides, it is a metabolite of Eslicarbazepine acetate, (BIA 2-093), a novel central nervous system drug.