Sodium benzoate, analytical standard

Base Information Edit

Chemical Name:Sodium benzoate, analytical standard
CAS No.:532-32-1
Molecular Formula:C7H5NaO2
Molecular Weight:144.105
Hs Code.:2916.31 Oral rat LD50: 4070 mg/kg
Mol file:532-32-1.mol

Synonyms:SCHEMBL128630;Sodium benzoate, LR, >=99%;Sodium benzoate, puriss., 99.5%;Sodium benzoate, analytical standard;s3750;Sodium benzoate, >=99%, FCC, FG;Sodium benzoate, BioXtra, >=99.5%;Sodium benzoate, ReagentPlus(R), 99%;Sodium benzoate, USP, 99.0-100.5%;Sodium benzoate, BioUltra, >=99.5% (NT);Sodium benzoate, SAJ first grade, >=98.5%;Sodium benzoate, SAJ special grade, >=99.0%;Sodium benzoate, purum p.a., >=99.0% (NT);Sodium benzoate, Vetec(TM) reagent grade, 98%;Sodium benzoate, certified reference material, TraceCERT(R);Sodium benzoate, United States Pharmacopeia (USP) Reference Standard;Sodium benzoate, Pharmaceutical Secondary Standard;Certified Reference Material

Suppliers and Price of Sodium benzoate, analytical standard

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Sodium benzoate
500g
$ 305.00

TCI Chemical
Sodium Benzoate [for Biochemical Research] >98.0%(HPLC)(T)
25g
$ 47.00

TCI Chemical
Sodium Benzoate >98.0%(HPLC)(T)
500g
$ 33.00

TCI Chemical
Sodium Benzoate [for Biochemical Research] >98.0%(HPLC)(T)
5g
$ 24.00

TCI Chemical
Sodium Benzoate >98.0%(HPLC)(T)
25g
$ 13.00

Sigma-Aldrich
Sodium benzoate analytical standard
47850
$ 18.60

Sigma-Aldrich
Sodium benzoate ReagentPlus , 99%
25g
$ 14.70

Sigma-Aldrich
Sodium benzoate purum p.a., ≥99.0% (NT)
250g
$ 21.10

Sigma-Aldrich
Sodium benzoate purum p.a., ≥99.0% (NT)
1kg
$ 45.20

Sigma-Aldrich
Sodium benzoate puriss., meets analytical specification of Ph.?Eur., BP, FCC, E211, 99.0-100.5% (calc. to the dried substance), powder
1 kg
$ 44.20

Total 588 raw suppliers

Chemical Property of Sodium benzoate, analytical standard Edit

Chemical Property:

Appearance/Colour:white crystalline powder
Vapor Pressure:0.0122mmHg at 25°C
Melting Point:>300 °C(lit.)
Boiling Point:249.3 °C at 760 mmHg
PKA:4.03[at 20 ℃]
Flash Point:111.4 °C
PSA：40.13000
Density:1,44 g/cm³
LogP:0.05010
Storage Temp.:Store at RT.
Solubility.:H2O: 1 M at 20 °C, clear, colorless
Water Solubility.:soluble
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:145.02654871
Heavy Atom Count:10
Complexity:104

Purity/Quality:

99%, ^*data from raw suppliers

Sodium benzoate ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi
Statements: 36/37/38-62-63-68-36
Safety Statements: 24/25-36-26

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Canonical SMILES:C1=CC=C(C=C1)C(=O)O.[Na]
Chemical Composition and Properties Sodium benzoate is an organic sodium salt derived from the substitution of the proton from the carboxy group of benzoic acid by a sodium ion. It is tasteless, odorless, and soluble in water. Due to its antibacterial and antifungal properties, it is widely utilized as a preservative in food and pharmaceutical products.
Regulatory Approval and Safety Sodium benzoate has been approved as a food preservative by regulatory authorities such as the Food and Drug Administration (FDA). It is generally regarded as safe (GRAS) when consumed in doses of less than 5 mg/kg of body weight per day, with an established Acceptable Daily Intake (ADI). The compound does not accumulate in the body and is metabolized into hippurate, primarily excreted through the urinary system.
Uses Sodium benzoate is commonly used to preserve food products with acidic pH levels, including fruit pulp, jams, pickles, margarine, beer, canned vegetables, and salads. It is often added to carbonated drinks, sauces, mayonnaises, tomato paste, and fruit preserves. Additionally, sodium benzoate occurs naturally in cinnamon, mushrooms, cranberries, blueberries, and cloves. Therapeutically, it is utilized in drugs for urea cycle disorders and hyperammonemia.
Potential Therapeutic Uses Studies suggest that sodium benzoate may have therapeutic potential beyond its preservative function. It has been investigated for its effects on major depressive disorder (MDD), schizophrenia, autism spectrum disorder (ASD), and neurodegenerative diseases. Sodium benzoate has been shown to reduce homocysteine levels, which are associated with MDD and anxiety. Furthermore, it exhibits anti-inflammatory effects and inhibits tryptophan degradation, potentially contributing to the treatment of MDD.
Effects in Animal Studies Sodium benzoate administration in animals has demonstrated effects on lipid profiles, and liver, and kidney parameters. It has been shown to reduce homocysteine levels and exhibit anti-inflammatory effects through modulation of the NF魏B factor. These findings suggest potential therapeutic implications for sodium benzoate in various diseases and conditions. However, further research is needed to fully understand its mechanisms of action and clinical applications.

Technology Process of Sodium benzoate, analytical standard

There total 122 articles about Sodium benzoate, analytical standard which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 100-51-6,185532-71-2
benzyl alcohol

: 532-32-1
sodium benzoate

Guidance literature:: With oxygen; sodium hydroxide; In neat (no solvent); at 179.84 ℃; for 8h; Reagent/catalyst;
DOI:10.1016/S1872-2067(14)60159-5

Reference yield: 81.0%

: 124-41-4
sodium methylate

: 582-24-1
1-phenyl-2-hydroxyethanone

: 532-32-1
sodium benzoate

: 50-00-0,30525-89-4,61233-19-0
formaldehyd

: 34557-54-5,27936-85-2
methane

: 108-88-3,15644-74-3,16713-13-6
toluene

Guidance literature:: In methanol; benzene; at 20 ℃; Product distribution; Kinetics; Rate constant;

Reference yield: 72.0%

: 3686-66-6
sodium p-chlorobenzoate

: 532-32-1
sodium benzoate

Guidance literature:: With Triethoxysilane; C₂₀H₂₄N₄Ni; sodium t-butanolate; In toluene; at 80 ℃; for 8h; Inert atmosphere; Schlenk technique;
DOI:10.1021/acs.organomet.7b00848