SODIUM P-CHLOROBENZOATE

Base Information

• Chemical Name: SODIUM P-CHLOROBENZOATE
• CAS No.: 3686-66-6
• Molecular Formula: C7H4ClNaO2
• Molecular Weight: 178.55
• Hs Code.: 2916399090
• Mol file: 3686-66-6.mol

Synonyms:Benzoicacid, 4-chloro-, sodium salt (9CI);Benzoic acid, p-chloro-, sodium salt (8CI);4-Chlorobenzoic acid sodium salt;Microbin;Microbine;Sodium 4-chlorobenzoate;Sodium p-chlorobenzoate;p-Chlorobenzoic acid sodium salt;

Chemical Property of SODIUM P-CHLOROBENZOATE

Chemical Property:

• Vapor Pressure: 0.00117mmHg at 25°C
• Melting Point: 243oC
• Boiling Point: 287.2 °C at 760 mmHg
• Flash Point: 127.5 °C
• PSA: 40.13000
• Density: 1.374g/cm3
• LogP: 0.70350

Purity/Quality:

98%Min ^*data from raw suppliers

Sodium4-Chlrobenzoate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Sodium 4-Chlrobenzoate is used in preparation method of antiviral active bagasse xylan cinnamate/m-chlorobenzoate.

Technology Process of SODIUM P-CHLOROBENZOATE

There total 16 articles about SODIUM P-CHLOROBENZOATE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

Methyl 4-chlorobenzoate (1126-46-1) + sodium trimethylsilanolate (18027-10-6) → sodium p-chlorobenzoate (3686-66-6)

Guidance literature:

In toluene;

Reference yield: 86.0%

Methyl 4-chlorobenzoate (1126-46-1) → sodium p-chlorobenzoate (3686-66-6)

Guidance literature:

With sodium trimethylsilanolate; In toluene; at 80 ℃; for 4h;

DOI:10.1016/S0040-4039(01)81697-X

Reference yield:

4-nitrophenol sodium salt (824-78-2) + para-chlorobenzoic acid (74-11-3) → 4-nitro-phenol (100-02-7,78813-13-5,89830-32-0) + sodium p-chlorobenzoate (3686-66-6)

Guidance literature:

With 1-butyl-2,3-dimethylimidazolium bis-(trifluoromethanesulfonyl)amide; In methanol; at 24.84 ℃; Reagent/catalyst; Equilibrium constant;

DOI:10.1021/jo100914p

upstream raw materials:

Methyl 4-chlorobenzoate

4-chlorophenacyl acetate

sodium methylate

1,2-bis(4-chlorophenyl)-2-oxoethyl acetate

Downstream raw materials:

2-<4-chlorobenzoyloxy>-1-(4-methoxyphenyl)-1-propanonen

4-Chloro-benzoic acid 2-oxo-2H-benzo[cd]indol-1-ylmethyl ester

4-chlorobenzoyl bromide

benzenesulfonic acid-(4-chloro-benzyl ester)

Refernces

• 1、 Kim, Mi Jin,Yang, Jung Woon. "One-pot synthesis of esters through a benzoin condensation-oxidative cleavage-esterification triple cascade reaction". . p. 3122 - 3124. Retrieved 2012/10/30.
• 2、 Ghosh, Kallol K.,Krishnani, Kishore K.,Ghosh, Sharmistha. "Effect of solvents on the kinetics and mechanism of the acidic and alkaline hydrolysis of hydroxamic acids". . p. 337 - 342. Retrieved 2007/10/03.