5-Methylphenazinium methosulfate

Base Information Edit

Chemical Name:5-Methylphenazinium methosulfate
CAS No.:299-11-6
Deprecated CAS:3130-59-4
Molecular Formula:C13H11N2^.CH3O4S
Molecular Weight:306.342
Hs Code.:29339900
European Community (EC) Number:206-072-1
NSC Number:34661
UNII:J3GYQ3401Y
DSSTox Substance ID:DTXSID1059783
Wikidata:Q27107674
Mol file:299-11-6.mol

Synonyms:5-methylphenazine; sulfonatooxymethane;Phenazine methosulfate;5-N-Methylphenazonium methosulfate;N-Methylphenazonium methosulphate;Phenazinium, 5-methyl-, methyl sulfate;N-Methylphenazinium methosulfate;5-methylphenazine;

Suppliers and Price of 5-Methylphenazinium methosulfate

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
Phenazine methosulfate 99+%
1g
$ 199.00

TRC
Phenazine methosulfate
500mg
$ 45.00

TCI Chemical
Phenazine Methyl Sulfate >98.0%(HPLC)(N)
5g
$ 86.00

TCI Chemical
Phenazine Methyl Sulfate [for Biochemical Research] >98.0%(HPLC)(N)
5g
$ 121.00

TCI Chemical
Phenazine Methyl Sulfate [for Biochemical Research] >98.0%(HPLC)(N)
1g
$ 39.00

TCI Chemical
Phenazine Methyl Sulfate >98.0%(HPLC)(N)
1g
$ 30.00

Sigma-Aldrich
Phenazine methosulfate ≥90% (UV)
1g
$ 48.80

Sigma-Aldrich
Phenazine methosulfate ≥90% (UV)
10g
$ 291.00

Sigma-Aldrich
Phenazine methosulfate ≥90% (UV)
25g
$ 546.00

Sigma-Aldrich
Phenazine methosulfate ≥90% (UV)
500mg
$ 28.40

Total 113 raw suppliers

Chemical Property of 5-Methylphenazinium methosulfate Edit

Chemical Property:

Appearance/Colour:orange to light brown crystals or powder
Melting Point:158-160 °C (dec.)(lit.)
Refractive Index:1.6930 (estimate)
PSA：91.58000
Density:1.3395 (rough estimate)
LogP:2.38630
Storage Temp.:2-8°C
Sensitive.:Light Sensitive
Solubility.:H2O: 0.2 g/mL at 20 °C, clear, deep orange
Water Solubility.:soluble
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:0
Exact Mass:306.06742811
Heavy Atom Count:21
Complexity:297

Purity/Quality:

99% ^*data from raw suppliers

Phenazine methosulfate 99+% ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xn,T,Xi
Hazard Codes:Xi,Xn,T
Statements: 36/37/38-68-46
Safety Statements: 26-36/37/39-53-45

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Chemical Classes:Nitrogen Compounds -> Other Aromatics (Nitrogen)
Canonical SMILES:C[N+]1=C2C=CC=CC2=NC3=CC=CC=C31.COS(=O)(=O)[O-]
Description Phenazine is a free radical generator. It has been used as an electron transfer reactant in cell viability assays. Phenazine (10 μM) induces ssDNA break formation in the presence of the reducing agent NADPH in a cell-free plasmid cleavage assay when used at a concentration of 10 μM. It induces oxidative DNA damage in an alkaline comet assay and apoptosis in A375 melanoma cells when used at a concentration of 10 μM. Phenazine (20 nM) oxidizes cysteine-containing proteins in HepG2 cells.
Uses As an electron carrier in place of the flavine enzyme of Warburg in the hexosemonophosphate system: Dickens, loc. cit. In the preparation of succinic dehydrogenase: Green et al., J. Biol. Chem. 217, 551 (1955). Phenazine Methosulfate is used in tyrosine transaminase test and for enzymic determination of ethanol in blood by the colorimetric micromethod. Used with ascorbic acid to determine nitric oxide reductase activity. Since the reduced PMS is easily oxidized by oxygen, it is used in assays as an electron carrier between enzymes and oxygen, cytochrome c, indophenols, or tetrazolium salts. The reduced PMS is used as an electron donor to reduce cytochrome c or in photosynthetic experiments. Usage of PMS for detection of specific dehydrogenases has been reported. Phenazine methosulfate is a compound used to determine nitric oxide reductase activity. Used in the discovery of potent bromophenazine antibacterial agents against Staphylococcus.

Technology Process of 5-Methylphenazinium methosulfate

There total 19 articles about 5-Methylphenazinium methosulfate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

: 92-82-0
Phenazin

: 77-78-1
dimethyl sulfate

: 299-11-6
phenazine methosulfate

Guidance literature:: In 1,2-dichloro-benzene; at 110 ℃; for 0.141667h; Flow reactor;
DOI:10.1002/ejoc.201900526

Reference yield:

: 119-75-5
2-nitro-N-phenylaniline

: 299-11-6
phenazine methosulfate

Guidance literature:: Multi-step reaction with 3 steps

1: alcohol; tin dichloride; fuming hydrochloric acid

2: sodium acetate / beim Erhitzen bis zum Sieden

3: nitrobenzene / 100 - 120 °C

With hydrogenchloride; ethanol; sodium acetate; nitrobenzene; tin(ll) chloride;

Reference yield:

: 62-53-3
aniline

: 299-11-6
phenazine methosulfate

Guidance literature:: Multi-step reaction with 4 steps

1: sodium acetate / 215 °C

2: alcohol; tin dichloride; fuming hydrochloric acid

3: sodium acetate / beim Erhitzen bis zum Sieden

4: nitrobenzene / 100 - 120 °C

With hydrogenchloride; ethanol; sodium acetate; nitrobenzene; tin(ll) chloride;