1,2-Bis(2-aminophenoxy)ethane

Base Information Edit

Chemical Name:1,2-Bis(2-aminophenoxy)ethane
CAS No.:52411-34-4
Molecular Formula:C14H16N2O2
Molecular Weight:244.293
Hs Code.:29215900
European Community (EC) Number:459-990-1,610-833-7
DSSTox Substance ID:DTXSID00365262
Nikkaji Number:J1.576.443K
Wikidata:Q72474734
ChEMBL ID:CHEMBL1708016
Mol file:52411-34-4.mol

Synonyms:52411-34-4;1,2-Bis(o-aminophenoxy)ethane;2,2'-(Ethylenedioxy)dianiline;1,2-Bis(2-aminophenoxy)ethane;2-[2-(2-aminophenoxy)ethoxy]aniline;1,2-Di(o-aminophenoxy)ethane;2-[2-(2-aminophenoxy)ethoxy]phenylamine;2,2'-(ethane-1,2-diylbis(oxy))dianiline;MFCD00087648;2,2'-[ethane-1,2-diylbis(oxy)]dianiline;2-(2-(2-aminophenoxy)ethoxy)phenylamine;2,2-(Ethylenedioxy)dianiline;BAPE;Enamine_001170;1,2,7,8-Dibenzo-1,8-diamino-3,6-dioxaoctane;Bis-(2-aminophenoxy)-ethane;MLS001195443;SCHEMBL864648;CHEMBL1708016;DTXSID00365262;HMS1397F04;HMS2859I03;BCP06902;STK792960;AKOS000115429;MS-2652;Ethylene Glycol Bis(2-aminophenyl) Ether;SMR000550754;SY067169;CS-0036462;E1365;EU-0017646;FT-0623079;EN300-02384;EC 459-990-1;Benzenamine,2,2'-(1,2-ethanediylbis(oxy))bis-;A870993;Benzenamine, 2,2'-[1,2-ethanediylbis(oxy)]bis-;Z56793625;1,2-Bis-(2-aminophenoxy)-ethane

Suppliers and Price of 1,2-Bis(2-aminophenoxy)ethane

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
1,2-Bis(2-aminophenoxy)ethane
25g
$ 1295.00

TCI Chemical
Ethylene Glycol Bis(2-aminophenyl) Ether >98.0%(HPLC)(T)
5g
$ 174.00

TCI Chemical
Ethylene Glycol Bis(2-aminophenyl) Ether >98.0%(HPLC)(T)
1g
$ 58.00

Medical Isotopes, Inc.
1,2-Bis(2-aminophenoxy)ethane
25 g
$ 2275.00

Medical Isotopes, Inc.
1,2-Bis(2-aminophenoxy)ethane
2.5 g
$ 650.00

Crysdot
1,2-Bis(o-aminophenoxy)ethane 97%
25g
$ 143.00

Chemenu
1,2-Bis(o-aminophenoxy)ethane 95+%
100g
$ 463.00

Chemenu
1,2-Bis(o-aminophenoxy)ethane 95+%
25g
$ 168.00

Biosynth Carbosynth
1,2-Bis(2-aminophenoxy)ethane
10 g
$ 660.70

Biosynth Carbosynth
1,2-Bis(2-aminophenoxy)ethane
1 g
$ 110.00

Total 74 raw suppliers

Chemical Property of 1,2-Bis(2-aminophenoxy)ethane Edit

Chemical Property:

Appearance/Colour:off-white crystalline solid
Vapor Pressure:2.16E-08mmHg at 25°C
Melting Point:131-132 °C
Refractive Index:1.631
Boiling Point:452.9 °C at 760 mmHg
PKA:4.56±0.10(Predicted)
Flash Point:253.5 °C
PSA：70.50000
Density:1.204 g/cm³
LogP:3.47120
Storage Temp.:under inert gas (nitrogen or Argon) at 2–8 °C
XLogP3:2.2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:5
Exact Mass:244.121177757
Heavy Atom Count:18
Complexity:214

Purity/Quality:

99% ^*data from raw suppliers

1,2-Bis(2-aminophenoxy)ethane ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:
Safety Statements: 24/25

MSDS Files:

Useful:

Canonical SMILES:C1=CC=C(C(=C1)N)OCCOC2=CC=CC=C2N

Technology Process of 1,2-Bis(2-aminophenoxy)ethane

There total 9 articles about 1,2-Bis(2-aminophenoxy)ethane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.6%

: 51661-19-9
1,2-bis(2-nitrophenoxy)ethane

: 52411-34-4
1,2-Bis(2-aminophenoxy)ethane

Guidance literature:: With palladium 10% on activated carbon; hydrogen; In N,N-dimethyl-formamide; at 70 - 80 ℃; for 20h;

Reference yield:

: 824-39-5
sodium o-nitrophenate

: 52411-34-4
1,2-Bis(2-aminophenoxy)ethane

Guidance literature:: Multi-step reaction with 2 steps

1: dimethylformamide

2: H₂ / Pd/C / ethanol

With hydrogen; palladium on activated charcoal; In ethanol; N,N-dimethyl-formamide;
DOI:10.1021/jf0201780

Reference yield:

: 88-75-5,78813-12-4
2-hydroxynitrobenzene

: 52411-34-4
1,2-Bis(2-aminophenoxy)ethane

Guidance literature:: Multi-step reaction with 2 steps

1: 75 percent / K₂CO₃ (calcined) / dimethylsulfoxide / 6 h / 130 °C

2: 91 percent / 85percent NH₂NH₂*H₂O / 5percent Pd/C / ethanol / 2 h / Heating

With potassium carbonate; hydrazine hydrate; palladium on activated charcoal; In ethanol; dimethyl sulfoxide;
DOI:10.1007/BF00475582